SCHEMBL29637740

SCHEMBL29637740

COCc1ncc(F)c(Nc2n[nH]c3c2CNC3(C)C)n1

nearest known ligand 0.53

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PRKCB P05771 20/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29637748 0.88 PRKCB (0.55) PRKCB
SCHEMBL29637730 0.84 PRKCB (0.56) PRKCB
SCHEMBL29637763 0.84 PRKCB (0.56) PRKCB
SCHEMBL21179291 0.82 PRKCB (0.53) PRKCB
SCHEMBL29637731 0.82 PRKCB (0.53) PRKCB
SCHEMBL29637749 0.81 PRKCB (0.58) PRKCB
SCHEMBL3325766 0.79 PRKCB (0.69) PRKCB
SCHEMBL28926306 0.77 PRKCB (0.65) PRKCB
SCHEMBL3326030 0.76 PRKCB (0.67) PRKCB
SCHEMBL29483939 0.76 PRKCB (0.67) PRKCB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220202815-A1 TREATMENT OF CANCER MINGSIGHT PHARMACEUTICALS, INC. 2022-06-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220202815-A1 TREATMENT OF CANCER PRKACB, PRKDC, PRKCH PRKCB 4/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.