SCHEMBL29637749

SCHEMBL29637749

CC1(C)NCc2c(Nc3nc(OCC(F)(F)F)ncc3F)n[nH]c21

nearest known ligand 0.58

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PRKCB P05771 19/20 0.58
PAK4 O96013 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29637730 0.89 PRKCB (0.56) PRKCBPAK4
SCHEMBL29637763 0.89 PRKCB (0.56) PRKCBPAK4
SCHEMBL29637748 0.82 PRKCB (0.55) PRKCBPAK4
SCHEMBL29637740 0.81 PRKCB (0.53) PRKCB
SCHEMBL21179291 0.80 PRKCB (0.53) PRKCBPAK4
SCHEMBL29637731 0.80 PRKCB (0.53) PRKCBPAK4
SCHEMBL3326180 0.74 PRKCB (1.00) PRKCB
SCHEMBL20503388 0.73 PRKCB (1.00) PRKCB
SCHEMBL29637747 0.73 PRKCB (1.00) PRKCB
SCHEMBL3323010 0.73 PRKCB (1.00) PRKCB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220202815-A1 TREATMENT OF CANCER MINGSIGHT PHARMACEUTICALS, INC. 2022-06-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220202815-A1 TREATMENT OF CANCER PRKACB, PRKDC, PRKCH PRKCB 4/4885PAK4 264/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.