⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7698024 | 0.75 | ALDH1A1 (0.50) | — | |
| SCHEMBL1922270 | 0.75 | ALDH1A1 (0.50) | — | |
| Benzene SCHEMBL28686547 | 0.71 | ALDH1A1 (0.45) | — | |
| SCHEMBL57468 | 0.71 | — | — | |
| SCHEMBL1259441 | 0.71 | — | — | |
| Water SCHEMBL11606806 | 0.71 | ALDH1A1 (0.45) | — | |
| SCHEMBL2462 | 0.71 | — | — | |
| SCHEMBL5536655 | 0.71 | — | — | |
| Water SCHEMBL11606809 | 0.71 | ALDH1A1 (0.45) | — | |
| SCHEMBL465339 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 217 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100227859-A1 | TRICYCLIC COMPOUNDS AS MATRIX METALLOPROTEINASE INHIBITORS | WYETH LLC | 2010-09-09 | — | — | US | claimed |
| EP-2144893-A2 | TRICYCLIC COMPOUNDS AS MATRIX METALLOPROTEINASE INHIBITORS | Wyeth a Corporation of the State of Delaware (US) | 2010-01-20 | — | — | EP | claimed |
| US-20080293674-A1 | Azinyl Imidazoazine and Azinyl Carboxamide | BAYER CROPSCIENCE AG (DE) | 2008-11-27 | — | — | US | claimed |
| WO-2008137816-A2 | TRICYCLIC COMPOUNDS AS MATRIX METALLOPROTEINASE INHIBITORS | WYETH (US) | 2008-11-13 | — | — | WO | claimed |
| EP-1751152-A2 | AZINYL IMIDAZOAZINE AND AZINYL CARBOXAMIDE | Bayer CropScience Aktiengesellschaft (DE) | 2007-02-14 | — | — | EP | claimed |
| US-20060281725-A1 | Agents and crystals for improving excretory potency of urinary bladder | ISIHARA YUJI | 2006-12-14 | — | — | US | claimed |
| EP-1604653-A1 | Acetylcholinesterase inhibitors for improving excretory potency of urinary bladder | Takeda Pharmaceutical Company Limited (JP) | 2005-12-14 | — | — | EP | claimed |
| WO-2005113553-A2 | AZINYL IMIDAZOAZINE AND AZINYL CARBOXAMIDE | BAYER CROPSCIENCE AG (DE) | 2005-12-01 | — | — | WO | claimed |
| US-20040116457-A1 | Agents for improving excretory potency of urinary bladder | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2004-06-17 | — | — | US | claimed |
| US-20020177593-A1 | Agents and crystals for improving excretory potency of urinary bladder | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2002-11-28 | — | — | US | claimed |
| EP-1118322-A1 | DRUGS FOR IMPROVING VESICAL EXCRETORY STRENGTH | Takeda Chemical Industries, Ltd. (JP) | 2001-07-25 | — | — | EP | claimed |
| US-6048890-A | WHICH DO NOT CAUSE LESIONS OF DIGESTIVE ORGANS | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 2000-04-11 | — | — | US | claimed |
| EP-0811620-A1 | PHENYLAMIDINOTHIOPHENE DERIVATIVES AND ANTIPHLOGISTIC AGENT CONTAINING THE SAME | Kaken Pharmaceutical Co., Ltd. (JP) | 1997-12-10 | — | — | EP | claimed |
| EP-0190105-A2 | Herbicidal agent | CIBA-GEIGY AG (CH) | 1986-08-06 | — | — | EP | claimed |
| CN-114796215-B | Application of tirofiban in preparing medicine for treating human respiratory syncytial virus infection | 贵州医科大学 | 2023-07-07 | — | — | CN | disclosed |
| US-20220401462-A1 | COMBINATION PREPARATIONS OF 3-N-FORMYLHYDROXYLAMINOPROPYL PHOSPHONIC ACID DERIVATIVES OR 3-N-ACETYLHYDROXYLAMINOPROPYL PHOSPHONIC ACID DERIVATIVES WITH CLINDAMYCIN AND ARTESUNATE | DMG DEUTSCHE MALARIA GMBH (DE) | 2022-12-22 | — | — | US | disclosed |
| WO-2021074452-A1 | COMBINATION PREPARATIONS OF 3-N-FORMYLHYDROXYLAMINOPROPYL PHOSPHONIC ACID DERIVATIVES OR 3-N-ACETYLHYDROXYLAMINOPROPYL PHOSPHONIC ACID DERIVATIVES WITH CLINDAMYCIN AND ARTESUNATE | DMG DEUTSCHE MALARIA GMBH (DE) | 2021-04-22 | — | — | WO | disclosed |
| US-4182758-A | BACTERICIDES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1980-01-08 | — | — | US | disclosed |
| US-4088785-A | HYPOTENSIVE AGENTS | WILLIAM H. RORER, INC. (US) | 1978-05-09 | — | — | US | disclosed |
| US-3931268-A | Methylhydrazinomethyl-substituted benzoic acid amides | HOFFMANN-LA ROCHE INC. (US) | 1976-01-06 | — | — | US | disclosed |