SCHEMBL29638100

SCHEMBL29638100

O=c1[nH]c(=S)[nH]cc1CNCCS(=O)(=O)O

nearest known ligand 0.42

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
KDM3B Q7LBC6 1/20 0.37
PNP P00491 4/20 0.35
UBE2N P61088 1/20 0.32
HPRT1 P00492 1/20 0.31
SLC2A1 P11166 1/20 0.31
CDK1 P06493 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30677850 0.85 LMNA (0.38) PNP
SCHEMBL15798435 0.76 KMT2A (0.44) KMT2ATDP1KDM3BPNPHPRT1
SCHEMBL29100444 0.74 KMT2A (0.45) KMT2ATDP1KDM3BPNP
SCHEMBL1227831 0.65 KMT2A (0.62) KMT2ATDP1KDM3BUBE2N
SCHEMBL153162 0.64 KMT2A (0.73) KMT2ATDP1KDM3B
SCHEMBL5618617 0.63 CHRM2 (0.61) KMT2A
SCHEMBL28991875 0.62 GAA (0.46)
SCHEMBL29007135 0.62 KMT2A (0.54) KMT2ATDP1KDM3BUBE2N
SCHEMBL1805336 0.61 PTGS1 (0.45)
SCHEMBL1981396 0.60 MEN1 (0.59) KMT2ATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026098357-A1 FREEZE-DRIED NUCLEIC ACID-LOADED LIPID NANOPARTICLE AND RECONSTITUTION METHOD THEREOF KUDO BIOTECHNOLOGY, INC. (US) 2026-05-15 WO disclosed
WO-2026088119-A1 LIPIDATED TLR7/8 MODULATORS AS ADJUVANTS AND USES THEREOF PFIZER INC. (US) 2026-04-30 WO disclosed
EP-4687990-A1 METHOD OF SYNTHESIS OF TARGETED LIPID NANOPARTICLE AND USES THEREOF OSE IMMUNOTHERAPEUTICS (FR) 2026-02-11 EP disclosed
EP-4665390-A1 IMMUNOGENIC COMPOSITION AGAINST INFLUENZA Pfizer Inc. (US) 2025-12-24 EP disclosed
EP-4662196-A1 IONIZABLE CATIONIC COMPOUND Seqirus Inc. (US) 2025-12-17 EP disclosed
EP-4661910-A2 IONIZABLE CATIONIC COMPOUND Seqirus Inc. (US) 2025-12-17 EP disclosed
EP-4658809-A1 CAPPING ASSAY Seqirus Inc. (US) 2025-12-10 EP disclosed
US-20250332245-A1 IMMUNOGENIC COMPOSITIONS AGAINST INFLUENZA PFIZER INC. (US) 2025-10-30 US disclosed
EP-4637717-A1 LIPID PARTICLE COMPOSITIONS AND METHODS OF USE THEREOF Pfizer Inc. (US) 2025-10-29 EP disclosed
EP-4637838-A1 LIPID NANOPARTICLE COMPOSITION Seqirus Inc. (US) 2025-10-29 EP disclosed
WO-2023067560-A1 IONIZABLE CATIONIC COMPOUND Seqirus Inc. (US) 2023-04-27 WO disclosed
WO-2023067561-A1 IONIZABLE CATIONIC LIPID FOR MESSENGER RNA DELIVERY Seqirus Inc. (US) 2023-04-27 WO disclosed
WO-2023057930-A1 IMMUNOGENIC LNP COMPOSITIONS AND METHODS THEREOF PFIZER INC. (US) 2023-04-13 WO disclosed
WO-2023053017-A2 IONIZABLE CATIONIC COMPOUNDS FOR MESSENGER RNA DELIVERY Seqirus Inc. (US) 2023-04-06 WO disclosed
WO-2023053016-A1 IONIZABLE CATIONIC COMPOUND Seqirus Inc. (US) 2023-04-06 WO disclosed
US-20220362372-A1 IMMUNOGENIC COMPOSITION AGAINST INFLUENZA PFIZER INC. 2022-11-17 US disclosed
WO-2022234417-A1 IMMUNOGENIC COMPOSITION AGAINST INFLUENZA PFIZER INC. (US) 2022-11-10 WO disclosed
WO-2022234416-A1 VACCINATION AGAINST PNEUMOCCOCAL AND COVID-19 INFECTIONS PFIZER INC. (US) 2022-11-10 WO disclosed
WO-2022234405-A1 VACCINATION AGAINST BACTERIAL AND BETACORONAVIRUS INFECTIONS PFIZER INC. (US) 2022-11-10 WO disclosed
WO-2022101461-A1 ENHANCED FORMULATION STABILIZATION AND IMPROVED LYOPHILIZATION PROCESSES BioNTech SE (DE) 2022-05-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250332245-A1 IMMUNOGENIC COMPOSITIONS AGAINST INFLUENZA HAVCR2, RNASEH1, ADAR KMT2A 3571/4885TDP1 619/4885KDM3B 4393/4885
US-20220362372-A1 IMMUNOGENIC COMPOSITION AGAINST INFLUENZA RNASEH1, HAVCR2, HNRNPH3 KMT2A 3179/4885TDP1 1120/4885KDM3B 4370/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.