Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYK2 | P29597 | 10/20 | 0.36 |
| ▸ | JAK1 | P23458 | 1/20 | 0.36 |
| ▸ | IGF1R | P08069 | 1/20 | 0.34 |
| ▸ | PRKDC | P78527 | 3/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.34 |
| ▸ | MTOR | P42345 | 2/20 | 0.34 |
| ▸ | TNK2 | Q07912 | 5/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29638416 | 0.88 | TYK2 (0.40) | TYK2JAK1 | |
| SCHEMBL29638376 | 0.88 | TYK2 (0.40) | TYK2JAK1 | |
| SCHEMBL24557269 | 0.88 | TYK2 (0.40) | TYK2JAK1 | |
| SCHEMBL27199230 | 0.88 | TYK2 (0.40) | TYK2JAK1 | |
| SCHEMBL29638471 | 0.86 | IDH1 (0.34) | TYK2JAK1PRKDC | |
| SCHEMBL29638329 | 0.84 | FGFR4 (0.36) | TYK2IGF1RTNK2 | |
| SCHEMBL24557308 | 0.83 | TYK2 (0.40) | TYK2JAK1PRKDCPIK3CAMTOR | |
| SCHEMBL29638445 | 0.83 | TYK2 (0.36) | TYK2JAK1IGF1R | |
| SCHEMBL24557292 | 0.83 | TYK2 (0.36) | TYK2JAK1IGF1R | |
| SCHEMBL29638404 | 0.83 | TYK2 (0.40) | TYK2JAK1PRKDCPIK3CAMTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022136914-A1 | TYK2 INHIBITORS AND USES THEREOF | SUDO BIOSCIENCES LIMITED (GB) | 2022-06-30 | — | — | WO | disclosed |