Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYK2 | P29597 | 8/20 | 0.36 |
| ▸ | JAK1 | P23458 | 1/20 | 0.34 |
| ▸ | BTK | Q06187 | 5/20 | 0.34 |
| ▸ | SRC | P12931 | 4/20 | 0.34 |
| ▸ | LYN | P07948 | 4/20 | 0.34 |
| ▸ | MAT2A | P31153 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | LCK | P06239 | 1/20 | 0.32 |
| ▸ | FYN | P06241 | 1/20 | 0.32 |
| ▸ | IGF1R | P08069 | 1/20 | 0.32 |
| ▸ | LTK | P29376 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.32 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.32 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.32 |
| ▸ | CLK2 | P49760 | 1/20 | 0.32 |
| ▸ | GSK3A | P49840 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24557292 | 1.00 | TYK2 (0.36) | TYK2JAK1BTKSRCLYN | |
| SCHEMBL29638414 | 0.87 | TYK2 (0.35) | TYK2JAK1BTKSRCLYN | |
| SCHEMBL29638404 | 0.86 | TYK2 (0.40) | TYK2JAK1MAPT | |
| SCHEMBL24557308 | 0.86 | TYK2 (0.40) | TYK2JAK1MAPT | |
| SCHEMBL29638416 | 0.84 | TYK2 (0.40) | TYK2JAK1PIK3C3 | |
| SCHEMBL24557269 | 0.84 | TYK2 (0.40) | TYK2JAK1PIK3C3 | |
| SCHEMBL27199230 | 0.84 | TYK2 (0.40) | TYK2JAK1SRCLYNMAPT | |
| SCHEMBL29638376 | 0.84 | TYK2 (0.40) | TYK2JAK1SRCLYNMAPT | |
| SCHEMBL29638394 | 0.83 | TYK2 (0.40) | TYK2JAK1BTKSRCLYN | |
| SCHEMBL27199231 | 0.83 | TYK2 (0.40) | TYK2JAK1BTKSRCLYN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022136914-A1 | TYK2 INHIBITORS AND USES THEREOF | SUDO BIOSCIENCES LIMITED (GB) | 2022-06-30 | — | — | WO | disclosed |