Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYK2 | P29597 | 20/20 | 0.59 |
| ▸ | JAK1 | P23458 | 2/20 | 0.58 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29638443 | 0.83 | TYK2 (0.51) | TYK2JAK1 | |
| SCHEMBL29638436 | 0.83 | TYK2 (0.51) | TYK2JAK1 | |
| SCHEMBL24557300 | 0.83 | TYK2 (0.51) | TYK2JAK1 | |
| SCHEMBL29638519 | 0.83 | TYK2 (0.45) | TYK2JAK1 | |
| SCHEMBL24557363 | 0.81 | TYK2 (0.45) | TYK2JAK1 | |
| SCHEMBL29638339 | 0.81 | TYK2 (0.45) | TYK2JAK1 | |
| SCHEMBL29638317 | 0.81 | TYK2 (0.42) | TYK2JAK1 | |
| SCHEMBL29638326 | 0.80 | TYK2 (0.46) | TYK2JAK1KCNH2 | |
| SCHEMBL28438070 | 0.80 | TYK2 (0.71) | TYK2JAK1 | |
| SCHEMBL29638361 | 0.79 | TYK2 (0.38) | TYK2JAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022136914-A1 | TYK2 INHIBITORS AND USES THEREOF | SUDO BIOSCIENCES LIMITED (GB) | 2022-06-30 | — | — | WO | disclosed |