Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 1/20 | 0.41 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.38 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.37 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.37 |
| ▸ | PRKDC | P78527 | 1/20 | 0.37 |
| ▸ | MAT2A | P31153 | 1/20 | 0.36 |
| ▸ | PHGDH | O43175 | 1/20 | 0.35 |
| ▸ | NSD2 | O96028 | 1/20 | 0.34 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.34 |
| ▸ | TYK2 | P29597 | 6/20 | 0.34 |
| ▸ | MAP3K12 | Q12852 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24557311 | 1.00 | PLK1 (0.41) | PLK1NOX4ABCG2SLC2A1PRKDC | |
| SCHEMBL24557251 | 0.89 | JAK2 (0.37) | ABCG2PRKDCTYK2MAP3K12 | |
| SCHEMBL29638415 | 0.89 | JAK2 (0.37) | ABCG2PRKDCTYK2MAP3K12 | |
| SCHEMBL24557361 | 0.86 | MAPT (0.45) | PLK1NOX4ABCG2PRKDCTYK2 | |
| SCHEMBL29638464 | 0.86 | NPC1 (0.41) | TYK2 | |
| SCHEMBL24557258 | 0.86 | NPC1 (0.41) | TYK2 | |
| SCHEMBL29638451 | 0.85 | TYK2 (0.39) | PLK1ABCG2TYK2 | |
| SCHEMBL24557263 | 0.85 | TYK2 (0.39) | PLK1ABCG2TYK2 | |
| SCHEMBL24557308 | 0.85 | TYK2 (0.40) | PLK1ABCG2PRKDCTYK2 | |
| SCHEMBL29638404 | 0.85 | TYK2 (0.40) | PLK1ABCG2PRKDCTYK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022136914-A1 | TYK2 INHIBITORS AND USES THEREOF | SUDO BIOSCIENCES LIMITED (GB) | 2022-06-30 | — | — | WO | disclosed |