Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 2/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.35 |
| ▸ | TYK2 | P29597 | 3/20 | 0.35 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.33 |
| ▸ | PRKDC | P78527 | 1/20 | 0.32 |
| ▸ | PIK3C3 | Q8NEB9 | 2/20 | 0.32 |
| ▸ | AR | P10275 | 2/20 | 0.32 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.30 |
| ▸ | KDM1A | O60341 | 2/20 | 0.30 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.30 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.30 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24557313 | 1.00 | CYP11B1 (0.35) | CYP11B1CYP11B2TYK2ABCG2PRKDC | |
| SCHEMBL24557293 | 0.89 | CYP11B2 (0.37) | CYP11B1CYP11B2TYK2AR | |
| SCHEMBL29638460 | 0.89 | CYP11B2 (0.37) | CYP11B1CYP11B2TYK2AR | |
| SCHEMBL29638479 | 0.89 | ABCG2 (0.41) | ABCG2AR | |
| SCHEMBL24557317 | 0.89 | ABCG2 (0.41) | ABCG2AR | |
| SCHEMBL29638471 | 0.88 | IDH1 (0.34) | TYK2PRKDCARMAP4K1 | |
| SCHEMBL24557251 | 0.86 | JAK2 (0.37) | TYK2ABCG2PRKDC | |
| SCHEMBL29638415 | 0.86 | JAK2 (0.37) | TYK2ABCG2PRKDC | |
| SCHEMBL24557311 | 0.83 | PLK1 (0.41) | TYK2ABCG2PRKDC | |
| SCHEMBL29638431 | 0.83 | PLK1 (0.41) | TYK2ABCG2PRKDC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022136914-A1 | TYK2 INHIBITORS AND USES THEREOF | SUDO BIOSCIENCES LIMITED (GB) | 2022-06-30 | — | — | WO | disclosed |