Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | TYK2 | P29597 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24557298 | 0.91 | TYK2 (0.38) | HPGDMAPTTYK2MEN1KMT2A | |
| SCHEMBL29638344 | 0.91 | TYK2 (0.38) | HPGDMAPTTYK2MEN1KMT2A | |
| SCHEMBL29638542 | 0.90 | TYK2 (0.37) | TYK2MEN1ALDH1A1KMT2AGAA | |
| SCHEMBL24557290 | 0.90 | TYK2 (0.37) | TYK2MEN1ALDH1A1KMT2AGAA | |
| SCHEMBL24557361 | 0.90 | MAPT (0.45) | HPGDMAPTTYK2MEN1KMT2A | |
| SCHEMBL24557258 | 0.89 | NPC1 (0.41) | HPGDMAPTTYK2MEN1ALDH1A1 | |
| SCHEMBL29638464 | 0.89 | NPC1 (0.41) | HPGDMAPTTYK2MEN1ALDH1A1 | |
| SCHEMBL29638414 | 0.88 | TYK2 (0.35) | HPGDMAPTTYK2CYP1A2CYP2C19 | |
| SCHEMBL24557251 | 0.87 | JAK2 (0.37) | HPGDMAPTTYK2CYP1A2CYP2C19 | |
| SCHEMBL29638468 | 0.87 | TRPV1 (0.39) | MAPTTYK2GAASMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022136914-A1 | TYK2 INHIBITORS AND USES THEREOF | SUDO BIOSCIENCES LIMITED (GB) | 2022-06-30 | — | — | WO | disclosed |