Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYK2 | P29597 | 5/20 | 0.46 |
| ▸ | JAK2 | O60674 | 1/20 | 0.46 |
| ▸ | ABL1 | P00519 | 5/20 | 0.45 |
| ▸ | GSK3B | P49841 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | CDK9 | P50750 | 1/20 | 0.44 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29638346 | 0.87 | ABL1 (0.47) | TYK2ABL1SMN1; SMN2 | |
| SCHEMBL24557316 | 0.87 | ABL1 (0.47) | TYK2ABL1SMN1; SMN2 | |
| SCHEMBL29638315 | 0.86 | ABL1 (0.46) | TYK2ABL1SMN1; SMN2 | |
| SCHEMBL24557318 | 0.86 | ABL1 (0.46) | TYK2ABL1SMN1; SMN2 | |
| SCHEMBL29638360 | 0.83 | TYK2 (0.50) | TYK2JAK2ABL1SMN1; SMN2 | |
| SCHEMBL29638382 | 0.82 | ABL1 (0.53) | TYK2JAK2ABL1GSK3BMEN1 | |
| SCHEMBL29638385 | 0.82 | ABL1 (0.47) | ABL1GSK3B | |
| SCHEMBL29638459 | 0.82 | ABL1 (0.55) | ABL1GSK3BMEN1KMT2A | |
| SCHEMBL29638373 | 0.79 | MAP4K1 (0.48) | ABL1GSK3B | |
| SCHEMBL28438070 | 0.79 | TYK2 (0.71) | TYK2JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022136914-A1 | TYK2 INHIBITORS AND USES THEREOF | SUDO BIOSCIENCES LIMITED (GB) | 2022-06-30 | — | — | WO | disclosed |