Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.53 |
| ▸ | GNG2 | P59768 | 1/20 | 0.42 |
| ▸ | GNB1 | P62873 | 1/20 | 0.42 |
| ▸ | CSNK1G1 | Q9HCP0 | 1/20 | 0.40 |
| ▸ | ROS1 | P08922 | 1/20 | 0.39 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.39 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.39 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5134183 | 0.87 | ALDH1A1 (0.43) | ALDH1A1KDM4EHSD17B10GNG2GNB1 | |
| SCHEMBL930322 | 0.84 | GNG2 (0.53) | ALDH1A1KDM4EHSD17B10GNG2GNB1 | |
| Hydrochloric Acid SCHEMBL27752534 | 0.84 | ALDH1A1 (0.41) | ALDH1A1KDM4EHSD17B10GNG2GNB1 | |
| SCHEMBL1612154 | 0.80 | ALDH1A1 (0.42) | ALDH1A1KDM4EHSD17B10GAAFGFR1 | |
| SCHEMBL1611442 | 0.80 | ALDH1A1 (0.42) | ALDH1A1KDM4EHSD17B10GAAFGFR1 | |
| Sulfuric Acid SCHEMBL4915014 | 0.80 | KDM4E (0.41) | ALDH1A1KDM4EHSD17B10GNG2GNB1 | |
| SCHEMBL11978695 | 0.79 | ALDH1A1 (0.41) | ALDH1A1KDM4EHSD17B10GAAFGFR1 | |
| Sulfuric Acid SCHEMBL4920843 | 0.78 | ALDH1A1 (0.39) | ALDH1A1KDM4EHSD17B10GNG2GNB1 | |
| SCHEMBL12374349 | 0.78 | ALDH1A1 (0.42) | ALDH1A1KDM4EHSD17B10GAAFGFR1 | |
| Sulfuric Acid SCHEMBL4925404 | 0.78 | GNG2 (0.55) | ALDH1A1KDM4EHSD17B10GNG2GNB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114591350-A | Compound containing spiro heterocyclic carbazole structure and application thereof | 北京燕化集联光电技术有限公司 | 2022-06-07 | — | — | CN | disclosed |