Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | GNG2 | P59768 | 1/20 | 0.33 |
| ▸ | GNB1 | P62873 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 5/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | CSNK1G1 | Q9HCP0 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 5/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5134183 | 0.93 | ALDH1A1 (0.43) | KDM4EALDH1A1HSD17B10GNG2GNB1 | |
| SCHEMBL863274 | 0.85 | ALDH1A1 (0.43) | KDM4EALDH1A1HSD17B10GNG2GNB1 | |
| SCHEMBL114129 | 0.84 | KDM4E (0.43) | KDM4EALDH1A1HSD17B10GNG2GNB1 | |
| Hydrochloric Acid SCHEMBL27752560 | 0.83 | KDM4E (0.42) | KDM4EALDH1A1HSD17B10GNG2GNB1 | |
| Hydrochloric Acid SCHEMBL30431952 | 0.83 | KDM4E (0.42) | KDM4EALDH1A1HSD17B10GNG2GNB1 | |
| SCHEMBL29638503 | 0.80 | ALDH1A1 (0.53) | KDM4EALDH1A1HSD17B10GNG2GNB1 | |
| Sulfuric Acid SCHEMBL4920843 | 0.79 | ALDH1A1 (0.39) | KDM4EALDH1A1HSD17B10GNG2GNB1 | |
| Sulfuric Acid SCHEMBL6207762 | 0.78 | KDM4E (0.42) | KDM4EALDH1A1HSD17B10GNG2GNB1 | |
| Sulfuric Acid SCHEMBL4925404 | 0.78 | GNG2 (0.55) | KDM4EALDH1A1HSD17B10GNG2GNB1 | |
| Hydrochloric Acid SCHEMBL27752534 | 0.75 | ALDH1A1 (0.41) | KDM4EALDH1A1HSD17B10GNG2GNB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080142370-A1 | Aqueous, Acidic Solution and Method for Electrolytically Depositing Copper Coatings as Well as Use of Said Solution | ATOTECH DEUTSCHLAND GMBH (DE) | 2008-06-19 | — | — | US | claimed |