Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRAF | P15056 | 8/20 | 0.33 |
| ▸ | LCK | P06239 | 6/20 | 0.33 |
| ▸ | TEK | Q02763 | 6/20 | 0.33 |
| ▸ | KDR | P35968 | 4/20 | 0.33 |
| ▸ | DHODH | Q02127 | 1/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.31 |
| ▸ | RAF1 | P04049 | 2/20 | 0.30 |
| ▸ | CSF1R | P07333 | 2/20 | 0.30 |
| ▸ | DDR1 | Q08345 | 2/20 | 0.30 |
| ▸ | DDR2 | Q16832 | 2/20 | 0.30 |
| ▸ | ARAF | P10398 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29638490 | 0.90 | MAPK14 (0.31) | BRAFMAPK14RAF1CSF1RDDR1 | |
| SCHEMBL29638669 | 0.82 | TNNI3K (0.35) | KDRMAPK14 | |
| SCHEMBL29638749 | 0.81 | BRAF (0.38) | BRAFLCKTEKKDR | |
| SCHEMBL29638623 | 0.79 | KDM1A (0.38) | BRAFLCKTEKKDRRAF1 | |
| SCHEMBL29638518 | 0.79 | FGFR1 (0.36) | BRAFKDRMAPK14RAF1 | |
| SCHEMBL29638508 | 0.79 | BRAF (0.35) | BRAFLCKTEKKDRRAF1 | |
| SCHEMBL29638706 | 0.76 | RAF1 (0.45) | BRAFRAF1CSF1RDDR1DDR2 | |
| SCHEMBL29638578 | 0.76 | RAF1 (0.43) | BRAFRAF1CSF1RDDR1DDR2 | |
| SCHEMBL29638666 | 0.75 | MAPK1 (0.36) | BRAFLCKTEKKDRRAF1 | |
| SCHEMBL29638567 | 0.75 | BRAF (0.36) | BRAFLCKTEKKDRMAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022089219-A1 | ARYLAMIDE COMPOUND, PHARMACEUTICAL COMPOSITION COMPRISING SAME, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 四川科伦博泰生物医药股份有限公司 | 2022-05-05 | — | — | WO | disclosed |