Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNNI3K | Q59H18 | 2/20 | 0.35 |
| ▸ | TGFBR1 | P36897 | 5/20 | 0.34 |
| ▸ | MAP4K4 | O95819 | 4/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.33 |
| ▸ | PIP4K2A | P48426 | 2/20 | 0.32 |
| ▸ | PIP4K2C | Q8TBX8 | 2/20 | 0.32 |
| ▸ | RIPK2 | O43353 | 2/20 | 0.32 |
| ▸ | KDR | P35968 | 2/20 | 0.32 |
| ▸ | RET | P07949 | 1/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.32 |
| ▸ | PKMYT1 | Q99640 | 1/20 | 0.32 |
| ▸ | PIP4K2B | P78356 | 1/20 | 0.31 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.31 |
| ▸ | CDK4 | P11802 | 2/20 | 0.31 |
| ▸ | CDK2 | P24941 | 2/20 | 0.31 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.30 |
| ▸ | PTK6 | Q13882 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | PIM1 | P11309 | 1/20 | 0.30 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29638490 | 0.83 | MAPK14 (0.31) | MAPK14 | |
| SCHEMBL29638645 | 0.82 | BRAF (0.33) | KDRMAPK14 | |
| SCHEMBL24399571 | 0.78 | TNNI3K (0.43) | TNNI3KTGFBR1MAP4K4P2RX7RIPK2 | |
| SCHEMBL30559487 | 0.78 | TNNI3K (0.43) | TNNI3KTGFBR1MAP4K4P2RX7RIPK2 | |
| SCHEMBL29638666 | 0.78 | MAPK1 (0.36) | KDRPIM1PIM2 | |
| SCHEMBL29638749 | 0.77 | BRAF (0.38) | TGFBR1KDR | |
| SCHEMBL29638518 | 0.76 | FGFR1 (0.36) | KDRMAPK14PIM1PIM2 | |
| SCHEMBL29638623 | 0.73 | KDM1A (0.38) | KDR | |
| SCHEMBL29638508 | 0.72 | BRAF (0.35) | MAP4K4KDRTDP1 | |
| SCHEMBL25373487 | 0.72 | ALDH3A1 (0.47) | TNNI3KTGFBR1MAP4K4P2RX7RIPK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022089219-A1 | ARYLAMIDE COMPOUND, PHARMACEUTICAL COMPOSITION COMPRISING SAME, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 四川科伦博泰生物医药股份有限公司 | 2022-05-05 | — | — | WO | disclosed |