Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.31 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2963160 | 0.78 | ALDH1A1 (0.31) | ALDH1A1MAPK1 | |
| SCHEMBL2959981 | 0.77 | DHFR (0.35) | ALDH1A1CYP2A6 | |
| SCHEMBL2970578 | 0.77 | ALDH1A1 (0.30) | ALDH1A1MAPK1 | |
| SCHEMBL2963036 | 0.77 | NISCH (0.38) | ALDH1A1MAPK1 | |
| SCHEMBL2965983 | 0.76 | KDM4E (0.31) | — | |
| SCHEMBL2962632 | 0.76 | ALDH1A1 (0.36) | ALDH1A1MAPK1ESR2CYP2A6CYP2B6 | |
| SCHEMBL2963377 | 0.75 | AKR1C3 (0.37) | ALDH1A1MAPK1ESR2CYP2A6CYP2B6 | |
| SCHEMBL2967877 | 0.75 | MEN1 (0.40) | ALDH1A1 | |
| SCHEMBL2974116 | 0.74 | MEN1 (0.30) | ALDH1A1 | |
| SCHEMBL2965788 | 0.73 | ALDH1A1 (0.38) | ALDH1A1MAPK1ESR2CYP2A6CYP2B6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2408927-B1 | PROBE COMPOUND FOR DETECTING AND ISOLATING ENZYMES AND MEANS AND METHODS USING THE SAME | HELMHOLTZ INFEKTIONSFORSCHUNG (DE) | 2013-11-27 | — | — | EP | disclosed |
| US-20120231972-A1 | Probe Compound for Detecting and Isolating Enzymes and Means and Methods Using the Same | INSTITUTE OF CATALYSIS (CSIC) (ES) | 2012-09-13 | — | — | US | disclosed |
| EP-2230312-A1 | Probe compound for detecting and isolating enzymes and means and methods using the same | Helmholtz-Zentrum für Infektionsforschung GmbH (DE) | 2010-09-22 | — | — | EP | disclosed |
| US-7763562-B2 | Heteroatom bridged metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2010-07-27 | — | — | US | disclosed |
| US-20070135597-A1 | Heteroatom bridged metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENTS INC. | 2007-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120231972-A1 | Probe Compound for Detecting and Isolating Enzymes and Means and Methods Using the Same | SI, GUSB, MPI | ALDH1A1 194/4885MAPK1 2285/4885ESR2 3186/4885 |
| US-20070135597-A1 | Heteroatom bridged metallocene compounds for olefin polymerization | AP2M1, AP1M1, PYM1 | ALDH1A1 4332/4885MAPK1 3118/4885ESR2 790/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.