SCHEMBL2963911

SCHEMBL2963911

CCCC1=CC(c2ccccc2)c2cccc(Br)c21

nearest known ligand 0.35

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
GID4 Q8IVV7 1/20 0.33
CACNA1D Q01668 1/20 0.31
KDM1A O60341 1/20 0.31
RCOR1 Q9UKL0 1/20 0.31
PBRM1 Q86U86 1/20 0.30
HDAC4 P56524 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2973832 0.76 GID4 (0.37) GID4KDM1APBRM1HDAC4
SCHEMBL2972658 0.75 CYP1A2 (0.35) CACNA1DKDM1ARCOR1
SCHEMBL2965503 0.72 MEN1 (0.35) CACNA1D
SCHEMBL2960702 0.66 PBRM1 (0.33) PBRM1
SCHEMBL2969029 0.65 CYSLTR2 (0.35) PBRM1
SCHEMBL2974663 0.65 KDM1A (0.33) GID4KDM1ARCOR1HDAC4
SCHEMBL2968111 0.64 ALDH1A1 (0.35)
SCHEMBL2957356 0.63 ALDH1A1 (0.32) KDM1ARCOR1PBRM1
SCHEMBL2965300 0.61 KDM4E (0.36) PBRM1
SCHEMBL2972130 0.61 GABRA1 (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7763562-B2 Heteroatom bridged metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2010-07-27 US disclosed
US-20070135597-A1 Heteroatom bridged metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. 2007-06-14 US disclosed
WO-2006065809-A2 HETEROATOM BRIDGED METALLOCENE COMPOUNDS FOR OLEFIN POLYMERIZATION EXXONMOBIL CHEMICAL PATENTS INC. (US) 2006-06-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070135597-A1 Heteroatom bridged metallocene compounds for olefin polymerization AP2M1, AP1M1, PYM1 GID4 2390/4885CACNA1D 3587/4885KDM1A 3280/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.