Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 9/20 | 0.81 |
| ▸ | POLB | P06746 | 3/20 | 0.81 |
| ▸ | MEN1 | O00255 | 2/20 | 0.81 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.81 |
| ▸ | MAPT | P10636 | 1/20 | 0.81 |
| ▸ | NAMPT | P43490 | 2/20 | 0.62 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 8/20 | 0.56 |
| ▸ | CASP3 | P42574 | 1/20 | 0.56 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.56 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.56 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.56 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.54 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.54 |
| ▸ | BAZ1A | Q9NRL2 | 2/20 | 0.54 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.54 |
| ▸ | CDK2 | P24941 | 1/20 | 0.54 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28741230 | 1.00 | NPC1 (0.81) | NPC1POLBMEN1KMT2AMAPT | |
| SCHEMBL651929 | 0.90 | NPC1 (1.00) | NPC1POLBMEN1KMT2AMAPT | |
| SCHEMBL31054249 | 0.90 | NPC1 (1.00) | NPC1POLBMEN1KMT2AMAPT | |
| SCHEMBL5658310 | 0.87 | NPC1 (0.88) | NPC1POLBMEN1KMT2AMAPT | |
| SCHEMBL5655823 | 0.84 | NPC1 (0.88) | NPC1POLBMEN1KMT2AMAPT | |
| SCHEMBL29639152 | 0.84 | RAB9A (0.64) | NPC1POLBMEN1KMT2AMAPT | |
| SCHEMBL28741178 | 0.84 | RAB9A (0.64) | NPC1POLBMEN1KMT2AMAPT | |
| SCHEMBL9189484 | 0.83 | NPC1 (0.74) | NPC1POLBMEN1KMT2AMAPT | |
| Hydrochloric Acid SCHEMBL9193053 | 0.82 | NPC1 (0.72) | NPC1POLBMEN1KMT2AMAPT | |
| SCHEMBL9189502 | 0.82 | MAPT (0.72) | NPC1POLBMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114436978-B | Antifungal compound and application thereof | 中国人民解放军海军军医大学 | 2024-06-18 | — | — | CN | disclosed |
| CN-114436978-A | Antifungal compound and application | 中国人民解放军海军军医大学 | 2022-05-06 | — | — | CN | disclosed |