SCHEMBL29639152

SCHEMBL29639152

O=C(Nc1cccc(O)c1)c1ccc2ncccc2c1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 6/20 0.64
NPC1 O15118 6/20 0.64
CASP3 P42574 1/20 0.64
SENP8 Q96LD8 1/20 0.64
SENP7 Q9BQF6 1/20 0.64
SENP6 Q9GZR1 1/20 0.64
PABPC1 P11940 1/20 0.64
POLB P06746 2/20 0.63
MAPT P10636 3/20 0.61
ALDH1A1 P00352 1/20 0.61
GAA P10253 1/20 0.61
PLK1 P53350 1/20 0.60
MEN1 O00255 4/20 0.60
KMT2A Q03164 4/20 0.60
HDAC1 Q13547 1/20 0.58
HDAC2 Q92769 1/20 0.58
BRAF P15056 1/20 0.55
TP53 P04637 1/20 0.55
MAPK1 P28482 1/20 0.55
ALOX15 P16050 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28741178 1.00 RAB9A (0.64) RAB9ANPC1CASP3SENP8SENP7
SCHEMBL6979265 0.85 BRAF (0.77) RAB9ANPC1CASP3SENP8SENP7
Hydrochloric Acid SCHEMBL7850629 0.85 PABPC1 (0.68) RAB9ANPC1CASP3SENP8SENP7
SCHEMBL28741230 0.84 NPC1 (0.81) RAB9ANPC1CASP3SENP8SENP7
SCHEMBL29639124 0.84 NPC1 (0.81) RAB9ANPC1CASP3SENP8SENP7
SCHEMBL7611676 0.82 RAB9A (0.61) RAB9ANPC1CASP3SENP8SENP7
SCHEMBL3657847 0.81 NPC1 (0.65) RAB9ANPC1POLBMAPTALDH1A1
SCHEMBL13702059 0.81 RAB9A (0.73) RAB9ANPC1CASP3SENP8SENP7
SCHEMBL1681165 0.81 NR1H4 (0.62) RAB9ANPC1CASP3SENP8SENP7
SCHEMBL29068810 0.80 DEGS1 (0.72) RAB9ANPC1CASP3SENP7SENP6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114436978-B Antifungal compound and application thereof 中国人民解放军海军军医大学 2024-06-18 CN disclosed
CN-114436978-A Antifungal compound and application 中国人民解放军海军军医大学 2022-05-06 CN disclosed