Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.59 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.58 |
| ▸ | PARP1 | P09874 | 4/20 | 0.54 |
| ▸ | TNKS | O95271 | 3/20 | 0.54 |
| ▸ | TNKS2 | Q9H2K2 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | GUSB | P08236 | 1/20 | 0.54 |
| ▸ | CASP3 | P42574 | 1/20 | 0.54 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.54 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.54 |
| ▸ | SERPINE1 | P05121 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12324316 | 0.86 | MAPK13 (0.50) | PTGS2PTGS1PARP1TNKSTNKS2 | |
| SCHEMBL853554 | 0.84 | SERPINE1 (0.72) | PTGS2PARP1TNKSTNKS2NPC1 | |
| SCHEMBL4770018 | 0.84 | PARP1 (0.54) | PTGS2PTGS1PARP1TNKSTNKS2 | |
| SCHEMBL29639192 | 0.84 | SERPINE1 (0.56) | PTGS2PTGS1TNKS2SERPINE1KDM4E | |
| SCHEMBL12323935 | 0.83 | PARP1 (0.57) | PTGS2PTGS1PARP1TNKSTNKS2 | |
| SCHEMBL29031852 | 0.82 | PTGS2 (0.56) | PTGS2PARP1TNKSTNKS2NPC1 | |
| SCHEMBL29639169 | 0.82 | PTGS2 (0.56) | PTGS2PARP1TNKSTNKS2NPC1 | |
| Indoxole SCHEMBL42592 | 0.82 | PTGS2 (0.76) | PTGS2PTGS1KDM4EALDH1A1SMN1; SMN2 | |
| Indoxole SCHEMBL29519430 | 0.82 | PTGS2 (0.76) | PTGS2PTGS1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL14867249 | 0.81 | KDM4E (0.50) | PTGS2PTGS1TNKSTNKS2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118496166-A | Preparation method of phthalazinone compound | 五邑大学 | 2024-08-16 | — | — | CN | disclosed |
| CN-113666925-B | Method for synthesizing isoindolo [2,1-b ] isoquinoline-5 (7H) -ketone compound | 广州大学 | 2022-05-17 | — | — | CN | disclosed |