SCHEMBL4770018

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL853554	0.84	SERPINE1 (0.72)	PARP1TNKSTNKS2NPC1RAB9A
	SCHEMBL29639239	0.84	PTGS2 (0.59)	PARP1TNKSTNKS2NPC1RAB9A
	SCHEMBL854032	0.84	PARP1 (0.62)	PARP1TNKSTNKS2NPC1RAB9A
	SCHEMBL12323935	0.83	PARP1 (0.57)	PARP1TNKSTNKS2NPC1RAB9A
	Hydrochloric Acid SCHEMBL854206	0.83	PARP1 (0.61)	PARP1TNKSTNKS2NPC1RAB9A
	SCHEMBL12323798	0.79	PARP1 (0.48)	PARP1TNKSTNKS2NPC1RAB9A
	SCHEMBL854577	0.77	POLB (0.51)	MAPT
	SCHEMBL1150241	0.73	ALDH1A1 (0.52)	PARP1TNKSTNKS2NPC1RAB9A
	SCHEMBL29639192	0.72	SERPINE1 (0.56)	TNKS2SERPINE1TUBB4ATUBBTUBA3C
	SCHEMBL28860747	0.71	PARP1 (0.66)	PARP1TNKSTNKS2NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.