SCHEMBL29639745

SCHEMBL29639745

CCCC(=O)c1ccc(O)c(C)c1O

nearest known ligand 0.55

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.55
KMT2A Q03164 4/20 0.55
MAPT P10636 1/20 0.55
SHBG P04278 1/20 0.53
HSD17B10 Q99714 3/20 0.52
ALDH1A1 P00352 2/20 0.52
ALOX15 P16050 2/20 0.52
HPGD P15428 1/20 0.52
TSHR P16473 1/20 0.52
RECQL P46063 1/20 0.52
TDP1 Q9NUW8 1/20 0.52
HTT P42858 2/20 0.51
NPC1 O15118 1/20 0.51
RAB9A P51151 1/20 0.51
GAA P10253 1/20 0.47
TCF4 P15884 1/20 0.47
CTNNB1 P35222 1/20 0.47
HSD17B3 P37058 1/20 0.44
FASN P49327 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4388031 1.00 MEN1 (0.55) MEN1KMT2AMAPTSHBGHSD17B10
SCHEMBL25284012 0.89 HTT (0.53) MEN1KMT2AMAPTSHBGHSD17B10
SCHEMBL9210604 0.88 HTT (0.59) MEN1KMT2AMAPTSHBGHSD17B10
SCHEMBL63797 0.85 ALDH1A1 (0.55) MEN1KMT2AMAPTHSD17B10ALDH1A1
SCHEMBL480863 0.85 MEN1 (0.58) MEN1KMT2AMAPTSHBGHSD17B10
SCHEMBL29639744 0.85 MEN1 (0.58) MEN1KMT2AMAPTSHBGHSD17B10
SCHEMBL30132562 0.84 SHBG (0.55) MEN1KMT2AMAPTSHBGHSD17B10
SCHEMBL20554833 0.84 SHBG (0.55) MEN1KMT2AMAPTSHBGHSD17B10
SCHEMBL2943808 0.80 HPGD (0.50) MEN1KMT2AMAPTHSD17B10ALDH1A1
SCHEMBL26384131 0.79 SHBG (0.58) MEN1KMT2AMAPTSHBGHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4452918-A1 METABOTROPIC GLUTAMATE RECEPTOR POSITIVE ALLOSTERIC MODULATORS (PAMS) AND USES THEREOF Sanford Burnham Prebys Medical Discovery Institute (US) 2024-10-30 EP disclosed
WO-2023122276-A1 METABOTROPIC GLUTAMATE RECEPTOR POSITIVE ALLOSTERIC MODULATORS (PAMS) AND USES THEREOF Sanford Burnham Prebys Medical Discovery Institute (US) 2023-06-29 WO disclosed
CN-114502659-A Resin composition, resin sheet, cured film, method for producing cured film, semiconductor device, organic EL display device, and display device 东丽株式会社 2022-05-13 CN disclosed