SCHEMBL480863

SCHEMBL480863

CCC(=O)c1ccc(O)c(C)c1O

nearest known ligand 0.58

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 6/20 0.58
KMT2A Q03164 6/20 0.58
MAPT P10636 2/20 0.58
SHBG P04278 1/20 0.55
HSD17B10 Q99714 3/20 0.54
ALOX15 P16050 1/20 0.54
NPC1 O15118 1/20 0.54
ALDH1A1 P00352 1/20 0.54
HTT P42858 1/20 0.54
RAB9A P51151 1/20 0.54
HSP90AB1 P08238 1/20 0.53
GAA P10253 1/20 0.49
POLB P06746 1/20 0.45
P4HB P07237 1/20 0.45
KDM4E B2RXH2 1/20 0.43
UBE2N P61088 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29639744 1.00 MEN1 (0.58) MEN1KMT2AMAPTSHBGHSD17B10
SCHEMBL4388031 0.85 MEN1 (0.55) MEN1KMT2AMAPTSHBGHSD17B10
SCHEMBL29639745 0.85 MEN1 (0.55) MEN1KMT2AMAPTSHBGHSD17B10
SCHEMBL7904832 0.84 HSP90AB1 (0.53) MEN1KMT2AMAPTSHBGHSD17B10
SCHEMBL9720621 0.84 HSP90AB1 (0.48) MEN1KMT2AMAPTSHBGHSD17B10
SCHEMBL2986601 0.83 HSP90AB1 (0.57) MEN1KMT2AMAPTHSD17B10ALOX15
SCHEMBL26384131 0.82 SHBG (0.58) MEN1KMT2AMAPTSHBGHSD17B10
SCHEMBL25284012 0.82 HTT (0.53) MEN1KMT2AMAPTSHBGHSD17B10
SCHEMBL27886877 0.81 HSP90AB1 (0.50) MEN1KMT2AMAPTSHBGHSD17B10
SCHEMBL16284308 0.81 HSP90AB1 (0.50) MEN1KMT2AMAPTSHBGHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200205541-A1 METHOD FOR STRAIGHTENING KERATINOUS FIBERS USING HEATING MEANS AND AN AROMATIC COMPOUND L'OREAL (FR) 2020-07-02 US claimed
US-20130298933-A1 METHOD FOR STRAIGHTENING KERATINOUS FIBERS USING HEATING MEANS AND AN AROMATIC COMPOUND L'OREAL (FR) 2013-11-14 US claimed
US-20100300472-A1 METHOD FOR STRAIGHTENING KERATINOUS FIBERS USING HEATING MEANS AND AN AROMATIC COMPOUND L'OREAL S.A. (FR) 2010-12-02 US claimed
EP-2925139-B1 FERMENTED SOIL ADDITIVE LIQUID FERTILISER SYSTEMS PTY LTD (AU) 2025-04-30 EP disclosed
US-20250064703-A1 COMPOSITION COMPRISING SOLUBILIZED POLYPHENOL OREAL (FR) 2025-02-27 US disclosed
US-20230398047-A1 COMPOSITION COMPRISING SKIN CARE ACTIVE INGREDIENT AND TWO POLYGLYCERYL FATTY ACID ESTERS L'OREAL (FR) 2023-12-14 US disclosed
WO-2023120260-A1 COMPOSITION COMPRISING SOLUBILIZED POLYPHENOL L'OREAL (FR) 2023-06-29 WO disclosed
EP-3393603-B1 TOPICAL DELIVERY SYSTEM FOR ACTIVE INGREDIENTS OREAL (FR) 2023-01-18 EP disclosed
EP-3656847-B1 ADDITIVE COMPOSITION FOR CULTURE MEDIUM, ADDITIVE COMPOUND FOR CULTURE MEDIUM, AND METHOD FOR CULTURE OF CELLS OR TISSUE USING SAME NISSAN CHEMICAL CORP (JP) 2022-08-17 EP disclosed
US-11399611-B2 Process for straightening keratin fibres with a heating means and denaturing agents L'OREAL (FR) 2022-08-02 US disclosed
US-20220144775-A1 HYDRAZIDE COMPOUND AND KINASE INHIBITOR NISSAN CHEMICAL CORPORATION (JP) 2022-05-12 US disclosed
US-20090318481-A1 Potentiators Of Glutamate Receptors AICHER THOMAS DANIEL 2009-12-24 US disclosed
US-7629400-B2 Image making medium HYMAN SYDNEY 2009-12-08 US disclosed
US-7598423-B2 Potentiators of glutamate receptors ELI LILLY AND COMPANY (US) 2009-10-06 US disclosed
US-20080139505-A1 Potentiators Of Glutamate Receptors ARRAY BIOPHARMA, INC. 2008-06-12 US disclosed
US-20080096930-A1 1-(2-hydroxy-3-methyl-4-{4-[4-(1H-tetrazol-5-yl)-pyridin-2-yloxy]-benzyloxy}-phenyl)-ethanone; 6-(3-((4-acetyl-3-hydroxy-2-propylphenoxy)methyl)phenylthio)isonicotinic acid; 1-(2-hydroxy-4-{3-[4-(2H-tetrazol-5-yl)-pyridin-2-yloxy]-benzyloxy}-3-trifluoromethyl-phenyl)-ethanone; treatment of migriane ARRAY BIOPHARMA, INC. 2008-04-24 US disclosed
US-20030035917-A1 Image making medium HYMAN SYDNEY (US) 2003-02-20 US disclosed
US-5703075-A Antiatherosclerotic and antithrombotic 1-benzopyran-4-ones and 2-amino-1,3-benzoxazine-4-ones PHARMACIA & UPJOHN COMPANY (US) 1997-12-30 US disclosed
EP-0459983-A1 ANTIATHEROSCLEROTIC AND ANTITHROMBOTIC 1-BENZOPYRAN-4-ONES AND 2-AMINO-1,3-BENZOXAZINE-4-ONES PHARMACIA & UPJOHN COMPANY (US) 1991-12-11 EP disclosed
WO-1990006921-A1 ANTIATHEROSCLEROTIC AND ANTITHROMBOTIC 1-BENZOPYRAN-4-ONES AND 2-AMINO-1,3-BENZOXAZINE-4-ONES THE UPJOHN COMPANY (US) 1990-06-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230398047-A1 COMPOSITION COMPRISING SKIN CARE ACTIVE INGREDIENT AND TWO POLYGLYCERYL FATTY ACID ESTERS ELOVL5, ELOVL3, LIPA MEN1 4516/4885KMT2A 1660/4885MAPT 3960/4885
US-20200205541-A1 METHOD FOR STRAIGHTENING KERATINOUS FIBERS USING HEATING MEANS AND AN AROMATIC COMPOUND KRT18, TUBB4A, TUBB4B MEN1 3792/4885KMT2A 889/4885MAPT 66/4885
US-20080139505-A1 Potentiators Of Glutamate Receptors GRM1, GRIN1, GRM2 MEN1 3851/4885KMT2A 3143/4885MAPT 3525/4885
US-11399611-B2 Process for straightening keratin fibres with a heating means and denaturing agents KRT18, KRTCAP2, TUBB4A MEN1 3718/4885KMT2A 1602/4885MAPT 90/4885
US-20220144775-A1 HYDRAZIDE COMPOUND AND KINASE INHIBITOR LATS1, LATS2, STK4 MEN1 3559/4885KMT2A 532/4885MAPT 2889/4885
US-20250064703-A1 COMPOSITION COMPRISING SOLUBILIZED POLYPHENOL PROC, GANC, LGALS1 MEN1 3653/4885KMT2A 4179/4885MAPT 2715/4885
US-20090318481-A1 Potentiators Of Glutamate Receptors GRIK1, GRIK2, GRIK4 MEN1 1909/4885KMT2A 2100/4885MAPT 2945/4885
US-20080096930-A1 1-(2-hydroxy-3-methyl-4-{4-[4-(1H-tetrazol-5-yl)-pyridin-2-yloxy]-benzyloxy}-phenyl)-ethanone; 6-(3-((4-acetyl-3-hydroxy-2-propylphenoxy)methyl)phenylthio)isonicotinic acid; 1-(2-hydroxy-4-{3-[4-(2H-tetrazol-5-yl)-pyridin-2-yloxy]-benzyloxy}-3-trifluoromethyl-phenyl)-ethanone; treatment of migriane HTR7, UGT2B7, HK1 MEN1 1199/4885KMT2A 2116/4885MAPT 1980/4885
US-20100300472-A1 METHOD FOR STRAIGHTENING KERATINOUS FIBERS USING HEATING MEANS AND AN AROMATIC COMPOUND KRT18, TUBB4A, TUBB4B MEN1 3792/4885KMT2A 889/4885MAPT 66/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.