Sangivamycin

Sangivamycin

SCHEMBL29639760

NC(=O)c1cn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c2ncnc(N)c12

nearest known ligand 0.82

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.82
GALR3 O60755 1/20 0.82
S1PR4 O95977 1/20 0.82
ALDH1A1 P00352 1/20 0.82
MAPT P10636 1/20 0.82
S1PR1 P21453 1/20 0.82
HTT P42858 1/20 0.82
RAB9A P51151 1/20 0.82
PAX8 Q06710 1/20 0.82
ADK P55263 12/20 0.72
DOT1L Q8TEK3 3/20 0.68
CDK1 P06493 1/20 0.62
CCNB1 P14635 1/20 0.62
CCNA2 P20248 1/20 0.62
CDK2 P24941 1/20 0.62
CCNA1 P78396 1/20 0.62
HIF1A Q16665 2/20 0.60
STAT6 P42226 2/20 0.60
DPP4 P27487 1/20 0.60
MEN1 O00255 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Sangivamycin SCHEMBL6731962 1.00 NPC1 (0.82) NPC1GALR3S1PR4ALDH1A1MAPT
Sangivamycin SCHEMBL10262607 1.00 NPC1 (0.82) NPC1GALR3S1PR4ALDH1A1MAPT
Sangivamycin SCHEMBL2786660 1.00 NPC1 (0.82) NPC1GALR3S1PR4ALDH1A1MAPT
Sangivamycin SCHEMBL29897938 1.00 NPC1 (0.82) NPC1GALR3S1PR4ALDH1A1MAPT
Sangivamycin SCHEMBL15107357 1.00 NPC1 (0.82) NPC1GALR3S1PR4ALDH1A1MAPT
Sangivamycin SCHEMBL12284269 1.00 NPC1 (0.82) NPC1GALR3S1PR4ALDH1A1MAPT
Sangivamycin SCHEMBL13065171 1.00 NPC1 (0.82) NPC1GALR3S1PR4ALDH1A1MAPT
Sangivamycin SCHEMBL14227089 1.00 NPC1 (0.82) NPC1GALR3S1PR4ALDH1A1MAPT
Sangivamycin SCHEMBL195540 1.00 NPC1 (0.82) NPC1GALR3S1PR4ALDH1A1MAPT
Sangivamycin SCHEMBL20141962 0.99 NPC1 (0.80) NPC1GALR3S1PR4ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260144879-A1 ANTI-VIRAL AND HEPATIC-TARGETED DRUGS AI-BIOPHARMA (FR) 2026-05-28 US claimed
US-20240139325-A1 ANTI-VIRAL AND HEPATIC-TARGETED DRUGS AI-BIOPHARMA (FR) 2024-05-02 US claimed
US-20230210848-A1 CORONAVIRUS INFECTION THERAPEUTIC AGENT FORMED THROUGH COMBINATION OF PYRAZINE DERIVATIVE AND ANOTHER CORONAVIRUS INFECTION THERAPEUTIC DRUG FUJIFILM TOYAMA CHEMICAL CO., LTD. (JP) 2023-07-06 US claimed
EP-4144353-A1 CORONAVIRUS INFECTION THERAPEUTIC AGENT FORMED THROUGH COMBINATION OF PYRAZINE DERIVATIVE AND ANOTHER CORONAVIRUS INFECTION THERAPEUTIC DRUG FUJIFILM Toyama Chemical Co., Ltd. (JP) 2023-03-08 EP claimed
EP-4100019-A1 METHOD FOR TREATING CORONAVIRUS INFECTIONS Oyagen Inc. (US) 2022-12-14 EP claimed
EP-4045504-A1 ANTI-VIRAL AND HEPATIC-TARGETED DRUGS Ai-biopharma (FR) 2022-08-24 EP claimed
CN-114901657-A Antiviral and liver-targeting drugs 人工智能生物制药公司 2022-08-12 CN claimed
US-20260144879-A1 ANTI-VIRAL AND HEPATIC-TARGETED DRUGS AI-BIOPHARMA (FR) 2026-05-28 US disclosed
WO-2026089014-A1 PREVENTIVE OR THERAPEUTIC AGENT AGAINST LIVESTOCK INFECTIOUS DISEASE CAUSED BY FOOT-AND-MOUTH DISEASE VIRUS 国立研究開発法人農業・食品産業技術総合研究機構 2026-04-30 WO disclosed
US-12539332-B2 Anti-viral and hepatic-targeted drugs A-BIOPHARMA (FR) 2026-02-03 US disclosed
US-20250243178-A1 3-(1,2,3,6-TETRAHYDROPYRIDIN-2-YL) PYRIDINE GLUTARATE OR A PHARMACEUTICALLY ACCEPTABLE SOLVATE THEREOF PHILIP MORRIS PRODUCTS S.A. (CH) 2025-07-31 US disclosed
US-12281093-B2 3-(1,2,3,6-tetrahydropyridin-2-YL) pyridine glutarate or a pharmaceutically acceptable solvate thereof PHILIP MORRIS PRODUCTS S.A. (CH) 2025-04-22 US disclosed
US-20240139325-A1 ANTI-VIRAL AND HEPATIC-TARGETED DRUGS AI-BIOPHARMA (FR) 2024-05-02 US disclosed
US-20230210848-A1 CORONAVIRUS INFECTION THERAPEUTIC AGENT FORMED THROUGH COMBINATION OF PYRAZINE DERIVATIVE AND ANOTHER CORONAVIRUS INFECTION THERAPEUTIC DRUG FUJIFILM TOYAMA CHEMICAL CO., LTD. (JP) 2023-07-06 US disclosed
EP-4144353-A1 CORONAVIRUS INFECTION THERAPEUTIC AGENT FORMED THROUGH COMBINATION OF PYRAZINE DERIVATIVE AND ANOTHER CORONAVIRUS INFECTION THERAPEUTIC DRUG FUJIFILM Toyama Chemical Co., Ltd. (JP) 2023-03-08 EP disclosed
EP-4100019-A1 METHOD FOR TREATING CORONAVIRUS INFECTIONS Oyagen Inc. (US) 2022-12-14 EP disclosed
EP-4045504-A1 ANTI-VIRAL AND HEPATIC-TARGETED DRUGS Ai-biopharma (FR) 2022-08-24 EP disclosed
CN-114901657-A Antiviral and liver-targeting drugs 人工智能生物制药公司 2022-08-12 CN disclosed
CN-114641299-A Methods for treating SARS CoV-2 infection 吉利德科学公司 2022-06-17 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12539332-B2 Anti-viral and hepatic-targeted drugs HAVCR2, NR1H4, NR1H3 NPC1 39/4885GALR3 1485/4885S1PR4 2484/4885
US-20230210848-A1 CORONAVIRUS INFECTION THERAPEUTIC AGENT FORMED THROUGH COMBINATION OF PYRAZINE DERIVATIVE AND ANOTHER CORONAVIRUS INFECTION THERAPEUTIC DRUG ACE2, ACE, SARS1 NPC1 1756/4885GALR3 3373/4885S1PR4 1908/4885
US-20260144879-A1 ANTI-VIRAL AND HEPATIC-TARGETED DRUGS HAVCR2, NR1H4, NR1H3 NPC1 25/4885GALR3 1362/4885S1PR4 2393/4885
US-12281093-B2 3-(1,2,3,6-tetrahydropyridin-2-YL) pyridine glutarate or a pharmaceutically acceptable solvate thereof ADH1A, GRHPR, GLS2 NPC1 2680/4885GALR3 830/4885S1PR4 1673/4885
US-20250243178-A1 3-(1,2,3,6-TETRAHYDROPYRIDIN-2-YL) PYRIDINE GLUTARATE OR A PHARMACEUTICALLY ACCEPTABLE SOLVATE THEREOF GLS2, ADH1A, GRHPR NPC1 2294/4885GALR3 806/4885S1PR4 1626/4885
US-20240139325-A1 ANTI-VIRAL AND HEPATIC-TARGETED DRUGS SLC10A1, HAVCR2, HDGF NPC1 22/4885GALR3 3574/4885S1PR4 3628/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.