Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 7/20 | 0.42 |
| ▸ | RPS6KA1 | Q15418 | 3/20 | 0.42 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.40 |
| ▸ | CCNE1 | P24864 | 4/20 | 0.40 |
| ▸ | CDK2 | P24941 | 4/20 | 0.40 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.38 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.37 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20908105 | 1.00 | MAPK1 (0.42) | MAPK1RPS6KA1APPS1PR3CCNE1 | |
| SCHEMBL5662378 | 0.88 | AAK1 (0.41) | MAPK1APPS1PR3AAK1ALDH1A1 | |
| SCHEMBL20907724 | 0.88 | AAK1 (0.41) | MAPK1APPS1PR3AAK1ALDH1A1 | |
| SCHEMBL20907493 | 0.85 | AAK1 (0.43) | S1PR3AAK1GAAKDM4EALDH1A1 | |
| SCHEMBL30557242 | 0.85 | AAK1 (0.43) | S1PR3AAK1GAAKDM4EALDH1A1 | |
| SCHEMBL28399677 | 0.85 | AAK1 (0.43) | S1PR3AAK1GAAKDM4EALDH1A1 | |
| SCHEMBL21112205 | 0.84 | CTSS (0.39) | S1PR3AAK1GAAKDM4EALDH1A1 | |
| SCHEMBL17844759 | 0.84 | AAK1 (0.47) | MAPK1AAK1GAAKDM4EALDH1A1 | |
| SCHEMBL20899699 | 0.84 | CTSS (0.39) | S1PR3AAK1GAAKDM4EALDH1A1 | |
| SCHEMBL20908005 | 0.83 | ATR (0.41) | MAPK1S1PR3AAK1GAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111212832-B | 1-Benzyl-2-imino-4-phenyl-5-oxoimidazolidine derivatives as HIV protease inhibitors | 吉利德科学公司 | 2023-09-15 | — | — | CN | disclosed |
| US-11352329-B2 | HIV protease inhibitors | GILEAD SCIENCES, INC. (US) | 2022-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11352329-B2 | HIV protease inhibitors | PRSS1, SERPINB1, FURIN | MAPK1 228/4885RPS6KA1 1978/4885APP 399/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.