Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARD | Q03181 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.38 |
| ▸ | PTGER3 | P43115 | 11/20 | 0.37 |
| ▸ | PTGFR | P43088 | 11/20 | 0.37 |
| ▸ | PTGIR | P43119 | 3/20 | 0.37 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.37 |
| ▸ | PTGER1 | P34995 | 3/20 | 0.36 |
| ▸ | PTGDR | Q13258 | 2/20 | 0.36 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SLCO2A1 | Q92959 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7017812 | 0.91 | ALDH1A1 (0.35) | ALDH1A1PPARGPPARDPPARAMEN1 | |
| SCHEMBL7021365 | 0.89 | ALDH1A1 (0.39) | ALDH1A1PPARGPPARDPPARAMEN1 | |
| SCHEMBL29640604 | 0.83 | ALDH1A1 (0.64) | ALDH1A1PPARGPPARDPPARAMEN1 | |
| SCHEMBL22687373 | 0.78 | PTGER2 (0.53) | ALDH1A1PPARGPPARDPPARAMEN1 | |
| SCHEMBL7021427 | 0.78 | PTGER2 (0.53) | ALDH1A1PPARGPPARDPPARAMEN1 | |
| SCHEMBL8567065 | 0.78 | PTGER4 (0.41) | ALDH1A1PPARGPPARDPPARAMEN1 | |
| SCHEMBL8567060 | 0.78 | PTGER4 (0.41) | ALDH1A1PPARGPPARDPPARAMEN1 | |
| SCHEMBL8564327 | 0.78 | PTGER4 (0.41) | ALDH1A1PPARGPPARDPPARAMEN1 | |
| SCHEMBL8564323 | 0.78 | PTGER4 (0.41) | ALDH1A1PPARGPPARDPPARAMEN1 | |
| SCHEMBL14562419 | 0.76 | TBXA2R (0.44) | ALDH1A1PPARGPPARDPPARAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0669329-B1 | Difluorprostacyclins, intermediates for production thereof and processes for production thereof | ASAHI GLASS CO LTD (JP) | 1998-05-20 | — | — | EP | disclosed |
| EP-0789022-A1 | Difluoroprostacyclins, intermediates for production thereof and process for production | ASAHI GLASS COMPANY LTD. (JP) | 1997-08-13 | — | — | EP | disclosed |