Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.67 |
| ▸ | MAOB | P27338 | 11/20 | 0.64 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | HTR2A | P28223 | 1/20 | 0.52 |
| ▸ | HTR2C | P28335 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | CASP7 | P55210 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6552997 | 1.00 | ALDH1A1 (0.67) | ALDH1A1KDM4EMAOBMAPTHTR2A | |
| SCHEMBL1821389 | 0.87 | MAPT (0.71) | ALDH1A1KDM4EMAOBMAPTNPC1 | |
| SCHEMBL6385719 | 0.81 | ALDH1A1 (0.69) | ALDH1A1KDM4EMAOBMAPTNPC1 | |
| SCHEMBL4728857 | 0.81 | KDM4E (0.69) | ALDH1A1KDM4EMAOBMAPTHTR2C | |
| SCHEMBL1983108 | 0.80 | ALDH1A1 (1.00) | ALDH1A1KDM4EMAOBMAPTHTR2C | |
| SCHEMBL1569957 | 0.80 | ALDH1A1 (0.67) | ALDH1A1KDM4EMAOBMAPTNPC1 | |
| SCHEMBL4727223 | 0.80 | ALDH1A1 (0.67) | ALDH1A1KDM4EMAOBMAPTNPC1 | |
| SCHEMBL2319848 | 0.80 | ALDH1A1 (0.67) | ALDH1A1KDM4EMAOBMAPTNPC1 | |
| SCHEMBL29922134 | 0.80 | ALDH1A1 (0.67) | ALDH1A1KDM4EMAOBMAPTNPC1 | |
| SCHEMBL29920457 | 0.80 | ALDH1A1 (0.67) | ALDH1A1KDM4EMAOBMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4658650-A1 | HETEROCYCLIC COMPOUNDS | Beone Medicines I GmbH (CH) | 2025-12-10 | — | — | EP | disclosed |
| WO-2024160277-A1 | HETEROCYCLIC COMPOUNDS | BEIGENE, LTD. (KY) | 2024-08-08 | — | — | WO | disclosed |
| CN-117897386-A | Benzopyran derivatives and uses thereof | 斯帕克生物制药有限公司 | 2024-04-16 | — | — | CN | disclosed |
| WO-2022188735-A1 | HETEROCYCLIC COMPOUNDS AS HPK1 INHIBITORS | GUANGDONG NEWOPP BIOPHARMACEUTICALS CO., LTD. (CN) | 2022-09-15 | — | — | WO | disclosed |
| CN-114929691-A | Bicyclic compounds and uses thereof | 爱思开生物制药株式会社 | 2022-08-19 | — | — | CN | disclosed |
| CN-114641477-A | Novel compound having inhibitory activity against glucose ceramide synthase or pharmaceutically acceptable salt thereof, method for preparing same, and pharmaceutical composition comprising same | 柳韩洋行 | 2022-06-17 | — | — | CN | disclosed |