Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 1/20 | 0.45 |
| ▸ | PPIA | P62937 | 1/20 | 0.43 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.43 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.43 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.43 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | TAS2R14 | Q9NYV8 | 2/20 | 0.41 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PLA2G2D | Q9UNK4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7962492 | 0.82 | CES1 (0.47) | CES1MAPK1LMNAHTTPLA2G2D | |
| SCHEMBL13727061 | 0.81 | POLB (0.50) | PPIAPDK2PDK1PDK3PDK4 | |
| SCHEMBL28454432 | 0.79 | POLB (0.45) | PPIAPDK2PDK1PDK3PDK4 | |
| Trifluoroacetic Acid SCHEMBL27851317 | 0.78 | KDM1A (0.48) | CES1PDK2PDK1PDK3PDK4 | |
| SCHEMBL6808202 | 0.78 | PPIA (0.43) | PPIAPDK2PDK1PDK3PDK4 | |
| SCHEMBL6276445 | 0.77 | PPIA (0.45) | CES1PPIAPOLBLMNAHSD11B1 | |
| SCHEMBL31000747 | 0.77 | PPIA (0.45) | CES1PPIAPOLBLMNAHSD11B1 | |
| SCHEMBL2913776 | 0.77 | ALDH1A1 (0.45) | PPIAPOLBLMNAHSD11B1MAPT | |
| SCHEMBL23037580 | 0.76 | ALDH1A1 (0.52) | PPIAPOLBLMNATAS2R14HTT | |
| SCHEMBL29365220 | 0.75 | ALDH1A1 (0.56) | PPIAPOLBLMNATAS2R14HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114450005-A | Compounds for the treatment of neurological disorders | 星座制药公司 | 2022-05-06 | — | — | CN | disclosed |