Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPIA | P62937 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | CES2 | O00748 | 3/20 | 0.44 |
| ▸ | CES1 | P23141 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31000747 | 1.00 | PPIA (0.45) | PPIAPOLBCES2CES1TSHR | |
| SCHEMBL15209960 | 0.92 | CES2 (0.56) | PPIAPOLBCES2CES1LMNA | |
| SCHEMBL8065818 | 0.89 | POLB (0.44) | PPIAPOLBCES2CES1TSHR | |
| SCHEMBL15180831 | 0.89 | POLB (0.44) | PPIAPOLBCES2CES1TSHR | |
| SCHEMBL31575826 | 0.86 | PPIA (0.43) | PPIAPOLBTSHRLMNAKDM4E | |
| SCHEMBL2913776 | 0.86 | ALDH1A1 (0.45) | PPIAPOLBTSHRLMNAKDM4E | |
| SCHEMBL29365220 | 0.84 | ALDH1A1 (0.56) | PPIAPOLBTSHRLMNAKDM4E | |
| SCHEMBL2164376 | 0.84 | PPIA (0.44) | PPIAPOLBTSHRLMNAKDM4E | |
| SCHEMBL180853 | 0.84 | ALDH1A1 (0.56) | PPIAPOLBTSHRLMNAKDM4E | |
| SCHEMBL23026097 | 0.82 | PPIA (0.43) | PPIAPOLBTSHRLMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005123754-A2 | TRANSITION-METAL CHARGE-TRANSPORT MATERIALS, METHODS OF FABRICATION THEREOF, AND METHODS OF USE THEREOF | GEORGIA TECH RESEARCH CORPORATION (US) | 2005-12-29 | — | — | WO | disclosed |