Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALCRL | Q16602 | 4/20 | 0.44 |
| ▸ | XIAP | P98170 | 1/20 | 0.44 |
| ▸ | CAPN1 | P07384 | 4/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | EPHA2 | P29317 | 2/20 | 0.43 |
| ▸ | NMUR2 | Q9GZQ4 | 1/20 | 0.41 |
| ▸ | CTSD | P07339 | 2/20 | 0.40 |
| ▸ | BACE1 | P56817 | 2/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
| ▸ | GRB2 | P62993 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | CMA1 | P23946 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29641620 | 0.92 | KDM1A (0.45) | CALCRLXIAPCAPN1EPHA2NMUR2 | |
| SCHEMBL30495673 | 0.87 | BACE1 (0.49) | CALCRLCAPN1CTSDBACE1KDM1A | |
| SCHEMBL30532203 | 0.86 | CALCRL (0.45) | CALCRLXIAPCAPN1CTSDBACE1 | |
| SCHEMBL30150556 | 0.86 | BACE1 (0.49) | CALCRLXIAPOPRM1CTSDBACE1 | |
| SCHEMBL30150576 | 0.85 | CALCRL (0.47) | CALCRLXIAPCAPN1OPRM1EPHA2 | |
| SCHEMBL30150591 | 0.85 | BACE1 (0.51) | CALCRLXIAPCTSDBACE1GRB2 | |
| SCHEMBL30495654 | 0.85 | CALCRL (0.52) | CALCRLXIAPEPHA2CTSDBACE1 | |
| SCHEMBL29641722 | 0.85 | GRB2 (0.48) | CALCRLXIAPCAPN1NMUR2CTSB | |
| SCHEMBL30311207 | 0.83 | XIAP (0.53) | CALCRLXIAPCAPN1GRB2CMA1 | |
| SCHEMBL29641583 | 0.83 | XIAP (0.59) | XIAPOPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220409709-A1 | LABYRINTHIN-BASED PEPTIDES FOR CANCER IMMUNOTHERAPIES AND USES THEREOF | LABYRX IMMUNOLOGIC THERAPEUTICS USA LTD (US) | 2022-12-29 | — | — | US | disclosed |
| US-20220089719-A1 | CONSTRUCTS TARGETING LABYRINTHIN OR A PORTION THEREOF AND USES THEREOF | LABYRX IMMUNOLOGIC THERAPEUTICS (USA) LIMITED (US) | 2022-03-24 | — | — | US | disclosed |