Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 6/20 | 0.51 |
| ▸ | CTSD | P07339 | 3/20 | 0.51 |
| ▸ | CALCRL | Q16602 | 4/20 | 0.45 |
| ▸ | KDM1A | O60341 | 3/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | KDM5A | P29375 | 1/20 | 0.45 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.45 |
| ▸ | EP300 | Q09472 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | F2 | P00734 | 2/20 | 0.41 |
| ▸ | XIAP | P98170 | 1/20 | 0.41 |
| ▸ | GRB2 | P62993 | 1/20 | 0.41 |
| ▸ | NPY1R | P25929 | 1/20 | 0.41 |
| ▸ | NPY2R | P49146 | 1/20 | 0.41 |
| ▸ | NPY4R | P50391 | 1/20 | 0.41 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30150556 | 0.96 | BACE1 (0.49) | BACE1CTSDCALCRLKDM1AMAOB | |
| SCHEMBL29641620 | 0.94 | KDM1A (0.45) | BACE1CTSDCALCRLKDM1AMAOB | |
| SCHEMBL30495673 | 0.91 | BACE1 (0.49) | BACE1CTSDCALCRLKDM1AMAOB | |
| SCHEMBL30150576 | 0.90 | CALCRL (0.47) | BACE1CTSDCALCRLF2XIAP | |
| SCHEMBL30512575 | 0.90 | NPY2R (0.49) | KDM1AMAOBKDM5AKDM1BEP300 | |
| SCHEMBL31182552 | 0.90 | BACE1 (0.47) | BACE1CTSDCALCRLEP300HIF1A | |
| SCHEMBL29727004 | 0.89 | AGTR2 (0.47) | BACE1CTSDCALCRLEP300HIF1A | |
| SCHEMBL29727005 | 0.89 | AGTR2 (0.47) | BACE1CTSDCALCRLEP300HIF1A | |
| SCHEMBL29733250 | 0.86 | CALCRL (0.47) | BACE1CTSDCALCRLXIAP | |
| SCHEMBL29379577 | 0.86 | GRB2 (0.50) | BACE1CTSDXIAPGRB2NPY1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220409709-A1 | LABYRINTHIN-BASED PEPTIDES FOR CANCER IMMUNOTHERAPIES AND USES THEREOF | LABYRX IMMUNOLOGIC THERAPEUTICS USA LTD (US) | 2022-12-29 | — | — | US | disclosed |