Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 9/20 | 0.49 |
| ▸ | CTSD | P07339 | 4/20 | 0.49 |
| ▸ | CALCRL | Q16602 | 4/20 | 0.47 |
| ▸ | KDM1A | O60341 | 2/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | KDM5A | P29375 | 1/20 | 0.42 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.42 |
| ▸ | F2R | P25116 | 2/20 | 0.42 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.42 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.42 |
| ▸ | XIAP | P98170 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30150591 | 0.96 | BACE1 (0.51) | BACE1CTSDCALCRLKDM1AMAOB | |
| SCHEMBL29641620 | 0.92 | KDM1A (0.45) | BACE1CTSDCALCRLKDM1AMAOB | |
| SCHEMBL29727004 | 0.90 | AGTR2 (0.47) | BACE1CTSDCALCRLAGTR1AGTR2 | |
| SCHEMBL29727005 | 0.90 | AGTR2 (0.47) | BACE1CTSDCALCRLAGTR1AGTR2 | |
| SCHEMBL30150576 | 0.89 | CALCRL (0.47) | BACE1CTSDCALCRLAGTR1AGTR2 | |
| SCHEMBL30495673 | 0.89 | BACE1 (0.49) | BACE1CTSDCALCRLKDM1AMAOB | |
| SCHEMBL31182552 | 0.89 | BACE1 (0.47) | BACE1CTSDCALCRL | |
| SCHEMBL29641646 | 0.87 | GRB2 (0.48) | BACE1CTSDCALCRLKDM1AAGTR1 | |
| SCHEMBL29641660 | 0.86 | CALCRL (0.44) | BACE1CTSDCALCRLKDM1AOPRM1 | |
| SCHEMBL29733250 | 0.85 | CALCRL (0.47) | BACE1CTSDCALCRLXIAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220409709-A1 | LABYRINTHIN-BASED PEPTIDES FOR CANCER IMMUNOTHERAPIES AND USES THEREOF | LABYRX IMMUNOLOGIC THERAPEUTICS USA LTD (US) | 2022-12-29 | — | — | US | disclosed |