Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALCRL | Q16602 | 5/20 | 0.47 |
| ▸ | CTSD | P07339 | 2/20 | 0.45 |
| ▸ | BACE1 | P56817 | 2/20 | 0.45 |
| ▸ | XIAP | P98170 | 1/20 | 0.44 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.44 |
| ▸ | RAMP1 | O60894 | 1/20 | 0.43 |
| ▸ | EPHA2 | P29317 | 2/20 | 0.43 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.42 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.42 |
| ▸ | GRB2 | P62993 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | CMA1 | P23946 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30150591 | 0.90 | BACE1 (0.51) | CALCRLCTSDBACE1XIAPGRB2 | |
| SCHEMBL29727005 | 0.90 | AGTR2 (0.47) | CALCRLCTSDBACE1XIAPAGTR1 | |
| SCHEMBL29727004 | 0.90 | AGTR2 (0.47) | CALCRLCTSDBACE1XIAPAGTR1 | |
| SCHEMBL30150556 | 0.89 | BACE1 (0.49) | CALCRLCTSDBACE1XIAPAGTR1 | |
| SCHEMBL29641660 | 0.85 | CALCRL (0.44) | CALCRLCTSDBACE1XIAPCAPN1 | |
| SCHEMBL29641620 | 0.85 | KDM1A (0.45) | CALCRLCTSDBACE1XIAPCAPN1 | |
| SCHEMBL30495673 | 0.85 | BACE1 (0.49) | CALCRLCTSDBACE1CAPN1 | |
| SCHEMBL29591883 | 0.85 | OPRM1 (0.49) | CALCRLCAPN1AGTR1AGTR2OPRM1 | |
| SCHEMBL32675731 | 0.84 | CAPN1 (0.51) | CALCRLCAPN1EPHA2 | |
| SCHEMBL31182552 | 0.84 | BACE1 (0.47) | CALCRLCTSDBACE1CAPN1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220409709-A1 | LABYRINTHIN-BASED PEPTIDES FOR CANCER IMMUNOTHERAPIES AND USES THEREOF | LABYRX IMMUNOLOGIC THERAPEUTICS USA LTD (US) | 2022-12-29 | — | — | US | disclosed |