Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 4/20 | 0.43 |
| ▸ | MYC | P01106 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.41 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | CFTR | P13569 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28437625 | 1.00 | TRPA1 (0.43) | TRPA1MYCKMT2APRMT5WDR77 | |
| SCHEMBL3628702 | 0.80 | P2RX4 (0.46) | TRPA1KMT2APRMT5WDR77MEN1 | |
| SCHEMBL4554015 | 0.76 | HCRTR1 (0.40) | TRPA1PRMT5WDR77ALDH1A1ATM | |
| SCHEMBL4552418 | 0.75 | P2RX4 (0.45) | KMT2AMEN1ALDH1A1ATMHDAC3 | |
| SCHEMBL6168375 | 0.75 | HSD17B3 (0.49) | KMT2AMEN1HDAC3MAPT | |
| SCHEMBL15056964 | 0.74 | HDAC3 (0.41) | KMT2AMEN1LMNATSHRALDH1A1 | |
| SCHEMBL29493251 | 0.74 | HDAC3 (0.41) | KMT2AMEN1LMNATSHRALDH1A1 | |
| SCHEMBL4553385 | 0.74 | MEN1 (0.45) | KMT2AMEN1KDM4EHDAC3SMN1; SMN2 | |
| SCHEMBL4430782 | 0.73 | KDM4E (0.43) | ALDH1A1KDM4EHDAC3HPGDSMN1; SMN2 | |
| SCHEMBL29950507 | 0.73 | HDAC3 (0.43) | KMT2AMEN1TSHRALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111333590-B | Preparation method of isoxazolidine hydrochloride | 沈阳中化农药化工研发有限公司 | 2022-05-17 | — | — | CN | disclosed |