Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | KDM5A | P29375 | 1/20 | 0.34 |
| ▸ | C1R | P00736 | 1/20 | 0.34 |
| ▸ | CES2 | O00748 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | LIPC | P11150 | 1/20 | 0.33 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.33 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21885675 | 1.00 | RXFP1 (0.43) | RXFP1MEN1KMT2AMAPTMAPK1 | |
| SCHEMBL10238280 | 0.79 | ALDH1A1 (0.50) | RXFP1MEN1KMT2AMAPTCA2 | |
| SCHEMBL27668346 | 0.77 | ALDH1A1 (0.40) | RXFP1MEN1KMT2AMAPTMAPK1 | |
| SCHEMBL4022589 | 0.76 | CES2 (0.46) | RXFP1MEN1KMT2AMAPTMAPK1 | |
| SCHEMBL1758557 | 0.76 | MEN1 (0.48) | RXFP1MEN1KMT2AMAPTMAPK1 | |
| SCHEMBL15955512 | 0.76 | ALDH1A1 (0.42) | MEN1KMT2AMAPTMAPK1CA2 | |
| SCHEMBL21885647 | 0.75 | TAS2R14 (0.49) | RXFP1MEN1KMT2AMAPTMAPK1 | |
| SCHEMBL29643298 | 0.75 | TAS2R14 (0.49) | RXFP1MEN1KMT2AMAPTMAPK1 | |
| SCHEMBL1758609 | 0.75 | ALDH1A1 (0.54) | MEN1KMT2AALDH1A1CYP2D6TRPV1 | |
| SCHEMBL24576209 | 0.75 | RXFP1 (0.40) | RXFP1MEN1KMT2AMAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115025086-A | Bicyclic heteroaryl derivatives, their preparation and use | 凯瑞康宁生物工程（武汉）有限公司 | 2022-09-09 | — | — | CN | disclosed |
| CN-110709386-B | Bicyclic heteroaryl derivatives, their preparation and use | 凯瑞康宁生物工程（武汉）有限公司 | 2022-06-07 | — | — | CN | disclosed |