Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 8/20 | 0.45 |
| ▸ | CHEK1 | O14757 | 6/20 | 0.45 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.45 |
| ▸ | PDPK1 | O15530 | 2/20 | 0.40 |
| ▸ | LRRK2 | Q5S007 | 3/20 | 0.37 |
| ▸ | LCK | P06239 | 1/20 | 0.37 |
| ▸ | CDK4 | P11802 | 1/20 | 0.37 |
| ▸ | CCND1 | P24385 | 1/20 | 0.37 |
| ▸ | CCND3 | P30281 | 1/20 | 0.37 |
| ▸ | MAPK13 | O15264 | 3/20 | 0.36 |
| ▸ | MAPK12 | P53778 | 3/20 | 0.36 |
| ▸ | MAPK11 | Q15759 | 3/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.36 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.34 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | GRK2 | P25098 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26979912 | 1.00 | KDR (0.45) | KDRCHEK1FGFR1PDPK1LRRK2 | |
| SCHEMBL13923958 | 0.86 | KDR (0.59) | KDRCHEK1FGFR1LCKCDK4 | |
| SCHEMBL17423781 | 0.82 | LMNA (0.53) | KDRCHEK1FGFR1LCKCDK4 | |
| SCHEMBL15792074 | 0.77 | ITK (0.47) | PDPK1MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL29644268 | 0.77 | PRKAG1 (0.47) | KDRCHEK1FGFR1LCKCDK4 | |
| SCHEMBL26980051 | 0.77 | PRKAG1 (0.47) | KDRCHEK1FGFR1LCKCDK4 | |
| SCHEMBL4061869 | 0.74 | KDR (0.41) | KDRCHEK1FGFR1LRRK2LCK | |
| SCHEMBL29644263 | 0.74 | KDM4E (0.55) | KDRCHEK1FGFR1 | |
| SCHEMBL26980773 | 0.74 | KDM4E (0.55) | KDRCHEK1FGFR1 | |
| SCHEMBL15505907 | 0.73 | LRRK2 (0.39) | KDRCHEK1FGFR1LRRK2PRMT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116867768-A | STING antagonists and uses thereof | 上海齐鲁锐格医药研发有限公司 | 2023-10-10 | — | — | CN | disclosed |
| EP-4247790-A1 | STING ANTAGONISTS AND USES THEREOF | Qilu Regor Therapeutics Inc. (CN) | 2023-09-27 | — | — | EP | disclosed |
| WO-2022105930-A1 | STING ANTAGONISTS AND USES THEREOF | QILU REGOR THERAPEUTICS INC. (CN) | 2022-05-27 | — | — | WO | disclosed |