Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.47 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.47 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.47 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.46 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.46 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.46 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.46 |
| ▸ | AHR | P35869 | 3/20 | 0.46 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.46 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.46 |
| ▸ | F7 | P08709 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.46 |
| ▸ | F3 | P13726 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1252143 | 1.00 | KDM1A (0.50) | KDM1AMAOAMAOBCYP17A1CYP11B1 | |
| SCHEMBL1570966 | 0.91 | KDM1A (0.47) | KDM1AMAOAMAOBCYP17A1CYP11B1 | |
| SCHEMBL1253354 | 0.85 | NLRP3 (0.48) | KDM1AMAOAMAOBAHRCYP2A6 | |
| SCHEMBL1570686 | 0.82 | SLC6A2 (0.55) | KDM1AMAOAMAOBCYP17A1CYP11B1 | |
| SCHEMBL14756111 | 0.82 | SLC6A2 (0.51) | KDM1AMAOAMAOBCYP17A1CYP11B1 | |
| SCHEMBL13428865 | 0.81 | KDM1A (0.47) | KDM1AMAOAMAOBCYP17A1CYP11B1 | |
| SCHEMBL763201 | 0.79 | AHR (0.50) | KDM1AMAOAMAOBCYP17A1CYP11B1 | |
| SCHEMBL29445647 | 0.79 | AHR (0.50) | KDM1AMAOAMAOBCYP17A1CYP11B1 | |
| SCHEMBL1044179 | 0.78 | ALKBH5 (0.47) | KDM1AMAOAMAOBCYP17A1CYP11B1 | |
| SCHEMBL10753454 | 0.78 | NFATC1 (0.61) | KDM1AMAOAMAOBALKBH5FTO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116867768-A | STING antagonists and uses thereof | 上海齐鲁锐格医药研发有限公司 | 2023-10-10 | — | — | CN | disclosed |
| EP-4247790-A1 | STING ANTAGONISTS AND USES THEREOF | Qilu Regor Therapeutics Inc. (CN) | 2023-09-27 | — | — | EP | disclosed |
| WO-2022105930-A1 | STING ANTAGONISTS AND USES THEREOF | QILU REGOR THERAPEUTICS INC. (CN) | 2022-05-27 | — | — | WO | disclosed |