Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.47 |
| ▸ | METAP2 | P50579 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | FGFR1 | P11362 | 5/20 | 0.46 |
| ▸ | CLK1 | P49759 | 1/20 | 0.46 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.46 |
| ▸ | BRAF | P15056 | 1/20 | 0.43 |
| ▸ | FGFR2 | P21802 | 2/20 | 0.42 |
| ▸ | FGFR3 | P22607 | 2/20 | 0.42 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26979386 | 1.00 | NOS1 (0.47) | NOS1MAPTDYRK1AMETAP2KDM4E | |
| SCHEMBL13923957 | 0.85 | FGFR1 (0.57) | NOS1MAPTDYRK1AMETAP2KDM4E | |
| SCHEMBL17423783 | 0.83 | FGFR1 (0.57) | NOS1MAPTDYRK1AMETAP2KDM4E | |
| SCHEMBL2933092 | 0.79 | NR4A1 (0.55) | NOS1MAPTDYRK1AMETAP2KDM4E | |
| SCHEMBL27975732 | 0.77 | MAPT (0.70) | NOS1MAPTDYRK1AMETAP2KDM4E | |
| SCHEMBL31052754 | 0.75 | KDM4E (0.60) | NOS1MAPTDYRK1AMETAP2KDM4E | |
| SCHEMBL20721442 | 0.75 | MAPT (0.53) | NOS1MAPTDYRK1AMETAP2KDM4E | |
| SCHEMBL252796 | 0.75 | KDM4E (0.60) | NOS1MAPTDYRK1AMETAP2KDM4E | |
| Hydrochloric Acid SCHEMBL29920009 | 0.74 | KDM4E (0.58) | NOS1MAPTDYRK1AMETAP2KDM4E | |
| SCHEMBL27976107 | 0.74 | CLK1 (0.74) | NOS1MAPTDYRK1AMETAP2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116867768-A | STING antagonists and uses thereof | 上海齐鲁锐格医药研发有限公司 | 2023-10-10 | — | — | CN | disclosed |
| EP-4247790-A1 | STING ANTAGONISTS AND USES THEREOF | Qilu Regor Therapeutics Inc. (CN) | 2023-09-27 | — | — | EP | disclosed |
| WO-2022105930-A1 | STING ANTAGONISTS AND USES THEREOF | QILU REGOR THERAPEUTICS INC. (CN) | 2022-05-27 | — | — | WO | disclosed |