Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.53 |
| ▸ | HPGD | P15428 | 5/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | ESR1 | P03372 | 1/20 | 0.53 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.53 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.53 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | GGT1 | P19440 | 1/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.53 |
| ▸ | BLM | P54132 | 1/20 | 0.53 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9217136 | 0.98 | KDM4E (0.51) | KDM4EALDH1A1HSD17B10HPGDTDP1 | |
| SCHEMBL11281805 | 0.86 | KDM4E (0.53) | KDM4EALDH1A1HSD17B10HPGDTDP1 | |
| SCHEMBL5404188 | 0.81 | ALDH1A1 (0.42) | KDM4EALDH1A1HSD17B10HPGDTDP1 | |
| SCHEMBL9770284 | 0.81 | KMT2A (0.55) | KDM4EALDH1A1HSD17B10HPGDTDP1 | |
| SCHEMBL9770258 | 0.81 | KMT2A (0.55) | KDM4EALDH1A1HSD17B10HPGDTDP1 | |
| SCHEMBL6990857 | 0.81 | KMT2A (0.55) | KDM4EALDH1A1HSD17B10HPGDTDP1 | |
| SCHEMBL212177 | 0.79 | KDM4E (0.58) | KDM4EALDH1A1HSD17B10HPGDTDP1 | |
| SCHEMBL27931686 | 0.79 | KDM4E (0.53) | KDM4EALDH1A1HSD17B10HPGDTDP1 | |
| SCHEMBL8893253 | 0.79 | KDM4E (0.51) | KDM4EALDH1A1HSD17B10HPGDTDP1 | |
| SCHEMBL144897 | 0.79 | KDM4E (0.57) | KDM4EALDH1A1HSD17B10HPGDTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117946028-B | Synthesis method of 1, 4-benzothiazepine compound | 南通大学 | 2024-09-24 | — | — | CN | claimed |
| CN-117946028-A | Synthesis method of 1, 4-benzothiazepine compound | 南通大学 | 2024-04-30 | — | — | CN | claimed |
| CN-117946028-B | Synthesis method of 1, 4-benzothiazepine compound | 南通大学 | 2024-09-24 | — | — | CN | disclosed |
| CN-117946028-A | Synthesis method of 1, 4-benzothiazepine compound | 南通大学 | 2024-04-30 | — | — | CN | disclosed |
| US-11584773-B2 | Phosphorous protecting groups and methods of preparation and use thereof | AGILENT TECHNOLOGIES, INC. (US) | 2023-02-21 | — | — | US | disclosed |
| EP-3943500-A1 | PHOSPHOROUS PROTECTING GROUPS AND METHODS OF PREPARATION AND USE THEREOF | Agilent Technologies, Inc. (US) | 2022-01-26 | — | — | EP | disclosed |
| US-20220002334-A1 | PHOSPHOROUS PROTECTING GROUPS AND METHODS OF PREPARATION AND USE THEREOF | UNIVERSITY OF COLORADO BOULDER | 2022-01-06 | — | — | US | disclosed |
| EP-3137478-B1 | PHOSPHOROUS PROTECTING GROUPS AND METHODS OF PREPARATION AND USE THEREOF | AGILENT TECHNOLOGIES INC (US) | 2021-09-22 | — | — | EP | disclosed |
| CN-106255697-B | Phosphorus protecting group and preparation method and application thereof | 安捷伦科技有限公司 | 2020-04-28 | — | — | CN | disclosed |
| US-20190194242-A1 | PHOSPHOROUS PROTECTING GROUPS AND METHODS OF PREPARATION AND USE THEREOF | UNIVERSITY OF COLORADO BOULDER | 2019-06-27 | — | — | US | disclosed |
| US-10196418-B2 | Phosphorous protecting groups and methods of preparation and use thereof | AGILENT TECHNOLOGIES, INC. (US) | 2019-02-05 | — | — | US | disclosed |
| EP-1514552-A1 | NOVEL FUSED IMIDAZOLE DERIVATIVE | Eisai Co., Ltd. (JP) | 2005-03-16 | — | — | EP | disclosed |
| EP-1246625-B1 | USES AND COMPOSITIONS OF NITRATE ESTERS FOR PROVIDING SEDATION | UNIV KINGSTON (CA) | 2004-12-01 | — | — | EP | disclosed |
| US-20040116328-A1 | Condensed imidazole derivatives | EISAI CO., LTD. (JP) | 2004-06-17 | — | — | US | disclosed |
| CN-1108287-C | Environmentally friendly process for preparing benzoic acid and its derivatives | SHANGHAI INST ORGANIC CHEM (CN) | 2003-05-14 | — | — | CN | disclosed |
| EP-1246625-A2 | METHODS AND COMPOSITIONS FOR MITIGATING PAIN USING NITRATE ESTERS | QUEEN'S UNIVERSITY AT KINGSTON (CA) | 2002-10-09 | — | — | EP | disclosed |
| WO-2001049275-A2 | METHODS AND COMPOSITIONS FOR MITIGATING PAIN USING NITRATE ESTERS | QUEEN'S UNIVERSITY AT KINGSTON (CA) | 2001-07-12 | — | — | WO | disclosed |
| CN-1296940-A | Environmentally friendly process for preparing benzoic acid and its derivatives | SHANGHAI INST ORGANIC CHEM (CN) | 2001-05-30 | — | — | CN | disclosed |
| US-5021491-A | Heat stabilizers for thermoplastic chloropolymers | CIBA-GEIGY CORPORATION (US) | 1991-06-04 | — | — | US | disclosed |
| US-3975395-A | PHOTOGRAPHIC ADDITIVE | FUJI PHOTO FILM CO., LTD. (JA) | 1976-08-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190194242-A1 | PHOSPHOROUS PROTECTING GROUPS AND METHODS OF PREPARATION AND USE THEREOF | POLN, POLRMT, NUDT21 | KDM4E 3963/4885ALDH1A1 3878/4885HSD17B10 4529/4885 |
| US-10196418-B2 | Phosphorous protecting groups and methods of preparation and use thereof | POLN, POLRMT, NUDT21 | KDM4E 3963/4885ALDH1A1 3878/4885HSD17B10 4529/4885 |
| US-20220002334-A1 | PHOSPHOROUS PROTECTING GROUPS AND METHODS OF PREPARATION AND USE THEREOF | POLN, POLRMT, NUDT21 | KDM4E 3963/4885ALDH1A1 3878/4885HSD17B10 4529/4885 |
| US-11584773-B2 | Phosphorous protecting groups and methods of preparation and use thereof | POLN, POLRMT, NUDT21 | KDM4E 3963/4885ALDH1A1 3878/4885HSD17B10 4529/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.