SCHEMBL29644495

SCHEMBL29644495

COc1ccc(CNc2cc(C)nc3c(-c4ccc5c(c4)c(C)nn5C)c(C)nn23)cc1

nearest known ligand 0.57

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
PI4KB Q9UBF8 7/20 0.57
NPY1R P25929 1/20 0.51
MAPT P10636 6/20 0.49
ALDH1A1 P00352 5/20 0.49
KDM4E B2RXH2 4/20 0.49
HPGD P15428 3/20 0.49
NPSR1 Q6W5P4 2/20 0.49
MEN1 O00255 1/20 0.49
KMT2A Q03164 1/20 0.49
CRHR1 P34998 3/20 0.48
MAPK1 P28482 2/20 0.47
CYP1A2 P05177 1/20 0.47
RAB9A P51151 1/20 0.45
TDP1 Q9NUW8 1/20 0.45
USP2 O75604 1/20 0.44
HSD17B10 Q99714 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20529103 1.00 PI4KB (0.57) PI4KBNPY1RMAPTALDH1A1KDM4E
SCHEMBL21628158 0.89 PI4KB (0.59) PI4KBMAPTALDH1A1KDM4EHPGD
SCHEMBL21628159 0.89 PI4KB (0.59) PI4KBMAPTALDH1A1KDM4EHPGD
SCHEMBL21628162 0.89 PI4KB (0.73) PI4KBMAPTALDH1A1KDM4EHPGD
SCHEMBL29644477 0.88 PI4KB (0.60) PI4KBMAPTALDH1A1KDM4EHPGD
SCHEMBL20528890 0.88 PI4KB (0.60) PI4KBMAPTALDH1A1KDM4EHPGD
SCHEMBL29644377 0.88 PI4KB (0.51) PI4KBNPY1RMAPTALDH1A1KDM4E
SCHEMBL20528899 0.88 PI4KB (0.51) PI4KBNPY1RMAPTALDH1A1KDM4E
SCHEMBL23387092 0.86 PI4KB (0.56) PI4KBMAPTALDH1A1KDM4EHPGD
SCHEMBL20529179 0.86 PI4KB (0.55) PI4KBMAPTALDH1A1KDM4EHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4676485-A1 COMPOUND AND FORMULATION FOR SYSTEMIC THERAPY BY ORAL TRANSMUCOSAL ADMINISTRATION CUROVIR AB (SE) 2026-01-14 EP claimed
WO-2024184442-A1 COMPOUND AND FORMULATION FOR SYSTEMIC THERAPY BY ORAL TRANSMUCOSAL ADMINISTRATION CUROVIR AB (SE) 2024-09-12 WO claimed
EP-4028131-A1 HETEROAROMATIC COMPOUNDS USEFUL IN THERAPY CUROVIR AB (SE) 2022-07-20 EP claimed
CN-110520424-B Heteroaromatic compounds for therapy 库洛维公司 2022-06-21 CN claimed
EP-4676485-A1 COMPOUND AND FORMULATION FOR SYSTEMIC THERAPY BY ORAL TRANSMUCOSAL ADMINISTRATION CUROVIR AB (SE) 2026-01-14 EP disclosed
WO-2024184442-A1 COMPOUND AND FORMULATION FOR SYSTEMIC THERAPY BY ORAL TRANSMUCOSAL ADMINISTRATION CUROVIR AB (SE) 2024-09-12 WO disclosed