SCHEMBL21628162

SCHEMBL21628162

Cc1cc(NCc2ccccc2)n2nc(C)c(-c3ccc4c(c3)c(C)nn4C)c2n1

nearest known ligand 0.73

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
PI4KB Q9UBF8 6/20 0.73
KDM4E B2RXH2 7/20 0.56
ALDH1A1 P00352 5/20 0.56
MAPT P10636 4/20 0.56
HPGD P15428 4/20 0.53
NPSR1 Q6W5P4 3/20 0.53
TDP1 Q9NUW8 3/20 0.53
LMNA P02545 2/20 0.53
HTT P42858 1/20 0.53
RAB9A P51151 4/20 0.52
MAPK1 P28482 2/20 0.52
ATM Q13315 1/20 0.50
MEN1 O00255 1/20 0.50
NPC1 O15118 1/20 0.50
KMT2A Q03164 1/20 0.50
USP2 O75604 1/20 0.46
HSD17B10 Q99714 1/20 0.46
GAA P10253 1/20 0.45
POLB P06746 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20528890 0.91 PI4KB (0.60) PI4KBKDM4EALDH1A1MAPTHPGD
SCHEMBL29644477 0.91 PI4KB (0.60) PI4KBKDM4EALDH1A1MAPTHPGD
SCHEMBL21628159 0.90 PI4KB (0.59) PI4KBKDM4EALDH1A1MAPTHPGD
SCHEMBL21628158 0.90 PI4KB (0.59) PI4KBKDM4EALDH1A1MAPTHPGD
SCHEMBL29644495 0.89 PI4KB (0.57) PI4KBKDM4EALDH1A1MAPTHPGD
SCHEMBL20529103 0.89 PI4KB (0.57) PI4KBKDM4EALDH1A1MAPTHPGD
SCHEMBL23387092 0.88 PI4KB (0.56) PI4KBKDM4EALDH1A1MAPTHPGD
SCHEMBL23024624 0.87 PI4KB (0.62) PI4KBKDM4EALDH1A1MAPTHPGD
SCHEMBL20529179 0.87 PI4KB (0.55) PI4KBKDM4EALDH1A1MAPTHPGD
SCHEMBL29715021 0.87 PI4KB (0.62) PI4KBKDM4EALDH1A1MAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4676485-A1 COMPOUND AND FORMULATION FOR SYSTEMIC THERAPY BY ORAL TRANSMUCOSAL ADMINISTRATION CUROVIR AB (SE) 2026-01-14 EP claimed
WO-2024184442-A1 COMPOUND AND FORMULATION FOR SYSTEMIC THERAPY BY ORAL TRANSMUCOSAL ADMINISTRATION CUROVIR AB (SE) 2024-09-12 WO claimed
EP-4028131-B1 HETEROAROMATIC COMPOUNDS USEFUL IN THERAPY CUROVIR AB (SE) 2023-11-22 EP claimed
EP-4028131-A1 HETEROAROMATIC COMPOUNDS USEFUL IN THERAPY CUROVIR AB (SE) 2022-07-20 EP claimed
EP-3606926-B1 HETEROAROMATIC COMPOUNDS USEFUL IN THERAPY CUROVIR AB (SE) 2021-05-26 EP claimed
WO-2021032611-A1 HETEROAROMATIC COMPOUNDS USEFUL IN THERAPY CUROVIR AB (SE) 2021-02-25 WO claimed
US-20200031833-A1 HETEROAROMATIC COMPOUNDS USEFUL IN THERAPY CUROVIR AB (SE) 2020-01-30 US claimed
EP-4676485-A1 COMPOUND AND FORMULATION FOR SYSTEMIC THERAPY BY ORAL TRANSMUCOSAL ADMINISTRATION CUROVIR AB (SE) 2026-01-14 EP disclosed
WO-2024184442-A1 COMPOUND AND FORMULATION FOR SYSTEMIC THERAPY BY ORAL TRANSMUCOSAL ADMINISTRATION CUROVIR AB (SE) 2024-09-12 WO disclosed
EP-4028131-B1 HETEROAROMATIC COMPOUNDS USEFUL IN THERAPY CUROVIR AB (SE) 2023-11-22 EP disclosed
EP-4028131-B1 HETEROAROMATIC COMPOUNDS USEFUL IN THERAPY CUROVIR AB (SE) 2023-11-22 EP disclosed
EP-3606926-B1 HETEROAROMATIC COMPOUNDS USEFUL IN THERAPY CUROVIR AB (SE) 2021-05-26 EP disclosed
EP-3606926-B1 HETEROAROMATIC COMPOUNDS USEFUL IN THERAPY CUROVIR AB (SE) 2021-05-26 EP disclosed
US-11001587-B2 Substituted indazoles as phosphatidylinositol kinase inhibitors CUROVIR AB (SE) 2021-05-11 US disclosed
US-11001587-B2 Substituted indazoles as phosphatidylinositol kinase inhibitors CUROVIR AB (SE) 2021-05-11 US disclosed
WO-2021032611-A1 HETEROAROMATIC COMPOUNDS USEFUL IN THERAPY CUROVIR AB (SE) 2021-02-25 WO disclosed
US-20200031833-A1 HETEROAROMATIC COMPOUNDS USEFUL IN THERAPY CUROVIR AB (SE) 2020-01-30 US disclosed
US-20200031833-A1 HETEROAROMATIC COMPOUNDS USEFUL IN THERAPY CUROVIR AB (SE) 2020-01-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11001587-B2 Substituted indazoles as phosphatidylinositol kinase inhibitors PIKFYVE, PI4KA, PIP4K2B PI4KB 6/4885KDM4E 3032/4885ALDH1A1 4239/4885
US-20200031833-A1 HETEROAROMATIC COMPOUNDS USEFUL IN THERAPY BECN1, SQSTM1, TFEB PI4KB 630/4885KDM4E 4130/4885ALDH1A1 1445/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.