SCHEMBL29644563

SCHEMBL29644563

Cc1ccc(NC(=O)Oc2ccccc2)cn1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.60
MAPT P10636 3/20 0.60
MEN1 O00255 2/20 0.56
KMT2A Q03164 2/20 0.56
KDM4E B2RXH2 2/20 0.56
THRB P10828 1/20 0.56
GFER P55789 1/20 0.56
TDP1 Q9NUW8 1/20 0.56
PORCN Q9H237 2/20 0.55
RAD51 Q06609 1/20 0.55
GAA P10253 3/20 0.55
LMNA P02545 1/20 0.55
TP53 P04637 1/20 0.55
HTT P42858 1/20 0.53
SMN1; SMN2 Q16637 1/20 0.53
FAAH O00519 6/20 0.52
MAPKAPK2 P49137 1/20 0.52
CYP1A2 P05177 1/20 0.51
POLB P06746 1/20 0.50
CCNE1 P24864 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1013306 1.00 ALDH1A1 (0.60) ALDH1A1MAPTMEN1KMT2AKDM4E
Hydrochloric Acid SCHEMBL29644534 0.98 ALDH1A1 (0.59) ALDH1A1MAPTMEN1KMT2AKDM4E
Hydrochloric Acid SCHEMBL31090358 0.98 ALDH1A1 (0.59) ALDH1A1MAPTMEN1KMT2AKDM4E
SCHEMBL29021371 0.85 ALDH1A1 (0.60) ALDH1A1MAPTMEN1KMT2AKDM4E
SCHEMBL24757867 0.84 ALDH1A1 (0.59) ALDH1A1MAPTMEN1KMT2AKDM4E
SCHEMBL20380072 0.84 NAMPT (0.56) ALDH1A1MAPTMEN1KMT2AKDM4E
SCHEMBL896314 0.83 KCNQ3 (0.64) ALDH1A1MAPTMEN1KMT2AKDM4E
SCHEMBL590618 0.82 KMT2A (0.61) ALDH1A1MAPTMEN1KMT2AKDM4E
SCHEMBL1010493 0.82 ALDH1A1 (0.56) ALDH1A1MAPTMEN1KMT2AKDM4E
SCHEMBL31728525 0.82 ALDH1A1 (0.56) ALDH1A1MAPTMEN1KMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2970123-B2 CRYSTALLINE DIHYDROCHLORIDE HYDRATE SALT OF OMECAMTIV MECARBIL AND PROCESS FOR ITS PREPARATION AMGEN INC (US) 2025-12-10 EP claimed
US-11958809-B2 Salt of omecamtiv mecarbil and process for preparing salt CYTOKINETICS, INC. (US) 2024-04-16 US claimed
US-20220153700-A1 SALT OF OMECAMTIV MECARBIL AND PROCESS FOR PREPARING SALT CYTOKINETICS, INC. 2022-05-19 US claimed
US-12583821-B2 Salt of omecamtiv mecarbil and process for preparing salt CYTOKINETICS, INC. (US) 2026-03-24 US disclosed
EP-2970123-B2 CRYSTALLINE DIHYDROCHLORIDE HYDRATE SALT OF OMECAMTIV MECARBIL AND PROCESS FOR ITS PREPARATION AMGEN INC (US) 2025-12-10 EP disclosed
US-20250243163-A1 SALT OF OMECAMTIV MECARBIL AND PROCESS FOR PREPARING SALT AMGEN INC. 2025-07-31 US disclosed
US-12221417-B2 Salt of omecamtiv mecarbil and process for preparing salt CYTOKINETICS, INC. (US) 2025-02-11 US disclosed
US-20240317687-A1 SALT OF OMECAMTIV MECARBIL AND PROCESS FOR PREPARING SALT CYTOKINETICS, INC. 2024-09-26 US disclosed
US-11958809-B2 Salt of omecamtiv mecarbil and process for preparing salt CYTOKINETICS, INC. (US) 2024-04-16 US disclosed
US-20240101517-A1 SALT OF OMECAMTIV MECARBIL AND PROCESS FOR PREPARING SALT AMGEN INC. 2024-03-28 US disclosed
US-20230044617-A1 SALT OF OMECAMTIV MECARBIL AND PROCESS FOR PREPARING SALT CYTOKINETICS, INC. 2023-02-09 US disclosed
US-11472773-B2 Salt of omecamtiv mecarbil and process for preparing salt CYTOKINETICS, INC. (US) 2022-10-18 US disclosed
US-20220153700-A1 SALT OF OMECAMTIV MECARBIL AND PROCESS FOR PREPARING SALT CYTOKINETICS, INC. 2022-05-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230044617-A1 SALT OF OMECAMTIV MECARBIL AND PROCESS FOR PREPARING SALT SI, SLC5A6, SLC28A1 ALDH1A1 1835/4885MAPT 2385/4885MEN1 348/4885
US-20250243163-A1 SALT OF OMECAMTIV MECARBIL AND PROCESS FOR PREPARING SALT SI, SLC5A6, SLC28A1 ALDH1A1 1835/4885MAPT 2385/4885MEN1 348/4885
US-20220153700-A1 SALT OF OMECAMTIV MECARBIL AND PROCESS FOR PREPARING SALT SI, SLC5A6, SLC28A1 ALDH1A1 1835/4885MAPT 2385/4885MEN1 348/4885
US-20240317687-A1 SALT OF OMECAMTIV MECARBIL AND PROCESS FOR PREPARING SALT SI, SLC5A6, SLC28A1 ALDH1A1 1835/4885MAPT 2385/4885MEN1 348/4885
US-11472773-B2 Salt of omecamtiv mecarbil and process for preparing salt SI, SLC5A6, SLC28A1 ALDH1A1 1835/4885MAPT 2385/4885MEN1 348/4885
US-20240101517-A1 SALT OF OMECAMTIV MECARBIL AND PROCESS FOR PREPARING SALT SI, SLC5A6, SLC28A1 ALDH1A1 1835/4885MAPT 2385/4885MEN1 348/4885
US-12583821-B2 Salt of omecamtiv mecarbil and process for preparing salt SLC28A2, SLC28A1, SLC5A11 ALDH1A1 1521/4885MAPT 1853/4885MEN1 252/4885
US-11958809-B2 Salt of omecamtiv mecarbil and process for preparing salt SI, SLC5A6, SLC28A1 ALDH1A1 1835/4885MAPT 2385/4885MEN1 348/4885
US-12221417-B2 Salt of omecamtiv mecarbil and process for preparing salt SI, SLC5A6, SLC28A1 ALDH1A1 1835/4885MAPT 2385/4885MEN1 348/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.