Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 5/20 | 0.67 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.63 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.63 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.48 |
| ▸ | ADK | P55263 | 1/20 | 0.46 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | MGLL | Q99685 | 1/20 | 0.43 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.43 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 2/20 | 0.42 |
| ▸ | IDH1 | O75874 | 1/20 | 0.42 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL794276 | 0.98 | PTGS2 (0.69) | PTGS2NR1H2NR1H3CAMK2DADK | |
| SCHEMBL710772 | 0.85 | NR1H2 (0.58) | PTGS2NR1H2NR1H3CAMK2DADK | |
| SCHEMBL28482238 | 0.83 | NR1H2 (0.56) | PTGS2NR1H2NR1H3CAMK2DADK | |
| SCHEMBL15451446 | 0.83 | NR1H2 (0.56) | PTGS2NR1H2NR1H3CAMK2DADK | |
| SCHEMBL15451447 | 0.83 | NR1H2 (0.56) | PTGS2NR1H2NR1H3CAMK2DADK | |
| SCHEMBL12725181 | 0.82 | NR1H2 (0.50) | PTGS2NR1H2NR1H3ADKPDE4B | |
| SCHEMBL5070001 | 0.79 | NR1H2 (0.52) | PTGS2NR1H2NR1H3CAMK2DADK | |
| SCHEMBL29644702 | 0.78 | PTGS2 (0.69) | PTGS2NR1H2NR1H3CASP3MGLL | |
| SCHEMBL15301616 | 0.77 | NR1H2 (0.50) | PTGS2NR1H2NR1H3CAMK2DADK | |
| SCHEMBL92524 | 0.77 | APP (0.57) | PTGS2NR1H2NR1H3CASP3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114456100-A | Method for preparing maleimide through cyclization of aryl acetaldehyde and primary amine | 长沙资材科技有限公司 | 2022-05-10 | — | — | CN | disclosed |