Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 7/20 | 0.69 |
| ▸ | NR1H2 | P55055 | 3/20 | 0.66 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.66 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.49 |
| ▸ | ADK | P55263 | 1/20 | 0.47 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.44 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.44 |
| ▸ | LCK | P06239 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29644690 | 0.98 | PTGS2 (0.67) | PTGS2NR1H2NR1H3CAMK2DADK | |
| SCHEMBL710772 | 0.87 | NR1H2 (0.58) | PTGS2NR1H2NR1H3CAMK2DADK | |
| SCHEMBL15451447 | 0.85 | NR1H2 (0.56) | PTGS2NR1H2NR1H3CAMK2DADK | |
| SCHEMBL28482238 | 0.85 | NR1H2 (0.56) | PTGS2NR1H2NR1H3CAMK2DADK | |
| SCHEMBL15451446 | 0.85 | NR1H2 (0.56) | PTGS2NR1H2NR1H3CAMK2DADK | |
| SCHEMBL5070001 | 0.81 | NR1H2 (0.52) | PTGS2NR1H2NR1H3CAMK2DADK | |
| SCHEMBL29644702 | 0.80 | PTGS2 (0.69) | PTGS2NR1H2NR1H3CASP3MAPT | |
| SCHEMBL12725181 | 0.79 | NR1H2 (0.50) | PTGS2NR1H2NR1H3ADKPDE4B | |
| SCHEMBL15301616 | 0.79 | NR1H2 (0.50) | PTGS2NR1H2NR1H3CAMK2DADK | |
| SCHEMBL6310937 | 0.78 | LCK (0.57) | PTGS2NR1H2NR1H3PDE4BCASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220213267-A1 | EXTREME HIGH TEMPERATURE STABLE ADHESIVES AND COATINGS | DESIGNER MOLECULES, INC | 2022-07-07 | — | — | US | disclosed |
| CN-114456100-A | Method for preparing maleimide through cyclization of aryl acetaldehyde and primary amine | 长沙资材科技有限公司 | 2022-05-10 | — | — | CN | disclosed |
| WO-2020215025-A1 | EXTREME HIGH TEMPERATURE STABLE ADHESIVES AND COATINGS | DESIGNER MOLECULES, INC (US) | 2020-10-22 | — | — | WO | disclosed |
| EP-2341915-B1 | PHOSPHORYLATED DENDRIMERS AS ANTIINFLAMMATORY DRUGS | CENTRE NAT RECH SCIENT (FR) | 2019-03-20 | — | — | EP | disclosed |
| EP-2439202-B1 | INHIBITOR COMPOUNDS OF 11-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 1 | SALVAT LAB SA (ES) | 2016-04-20 | — | — | EP | disclosed |
| US-8822452-B2 | Inhibitor compounds of 11-beta-hydroxysteroid dehydrogenase type 1 | LABORATORIOS SALVAT, S.A. (ES) | 2014-09-02 | — | — | US | disclosed |
| US-20130303522-A1 | INHIBITOR COMPOUNDS OF 11-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 1 | LABORATORIOS SALVAT, S.A. (ES) | 2013-11-14 | — | — | US | disclosed |
| US-20130303522-A1 | INHIBITOR COMPOUNDS OF 11-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 1 | LABORATORIOS SALVAT, S.A. (ES) | 2013-11-14 | — | — | US | disclosed |
| US-8524894-B2 | Inhibitor compounds of 11-beta-hydroxysteroid dehydrogenase type 1 | LABORATORIOS SALVAT, S.A. (ES) | 2013-09-03 | — | — | US | disclosed |
| EP-1771548-B1 | USE OF DENDRIMERS TO STIMULATE CELL GROWTH | CENTRE NAT RECH SCIENT (FR) | 2012-06-27 | — | — | EP | disclosed |
| US-7662308-B2 | Polyhedral oligomeric silsesquioxane (POSS) based fluorescent colorants | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2010-02-16 | — | — | US | disclosed |
| WO-2010013086-A1 | PHOSPHORYLATED DENDRIMERS AS ANTIINFLAMMATORY DRUGS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2010-02-04 | — | — | WO | disclosed |
| EP-2049601-B1 | NOVEL POLYHEDRAL OLIGOMERIC SILSESQUIOXANE (POSS) BASED FLUORESCENT COLORANTS | BASF SE (DE) | 2009-12-09 | — | — | EP | disclosed |
| US-20090048236-A1 | NEW PHENYLALANINE DERIVATIVES | AJINOMOTO CO. INC (JP) | 2009-02-19 | — | — | US | disclosed |
| US-20090048236-A1 | NEW PHENYLALANINE DERIVATIVES | AJINOMOTO CO. INC (JP) | 2009-02-19 | — | — | US | disclosed |
| US-7452905-B2 | Phenylalanine derivatives | AJINOMOTO CO., INC. (JP) | 2008-11-18 | — | — | US | disclosed |
| US-7452905-B2 | Phenylalanine derivatives | AJINOMOTO CO., INC. (JP) | 2008-11-18 | — | — | US | disclosed |
| WO-2008017593-A1 | NOVEL POLYHEDRAL OLIGOMERIC SILSESQUIOXANE (POSS) BASED FLUORESCENT COLORANTS | CIBA HOLDING INC. (CH) | 2008-02-14 | — | — | WO | disclosed |
| US-20080029739-A1 | Novel polyhedral oligomeric silsesquioxane (POSS) based fluorescent colorants | CIBA SPECIALTY CHEMICALS CORP. | 2008-02-07 | — | — | US | disclosed |
| US-20080029739-A1 | Novel polyhedral oligomeric silsesquioxane (POSS) based fluorescent colorants | CIBA SPECIALTY CHEMICALS CORP. | 2008-02-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090048236-A1 | NEW PHENYLALANINE DERIVATIVES | ITGB4, VCAM1, ITGA4 | PTGS2 2667/4885NR1H2 2265/4885NR1H3 1685/4885 |
| US-20130303522-A1 | INHIBITOR COMPOUNDS OF 11-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 1 | HSD11B1, HSD17B1, HSD11B2 | PTGS2 272/4885NR1H2 36/4885NR1H3 39/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.