Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADK | P55263 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 6/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | C1R | P00736 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29645760 | 0.85 | MAPT (0.56) | POLBKDM4EALDH1A1KMT2AHCRTR1 | |
| SCHEMBL29645430 | 0.85 | NPC1 (0.48) | ADKPOLBKDM4EALDH1A1MEN1 | |
| SCHEMBL29645658 | 0.82 | ADORA3 (0.51) | ADKPOLBKDM4EALDH1A1MAPT | |
| SCHEMBL29645950 | 0.80 | MAPT (0.41) | ADKPOLBMEN1KMT2AMAPT | |
| SCHEMBL29645834 | 0.80 | ADORA3 (0.49) | POLBKDM4EALDH1A1KMT2AHCRTR1 | |
| SCHEMBL29645636 | 0.80 | MAPT (0.47) | ADKPOLBALDH1A1MEN1KMT2A | |
| SCHEMBL29645533 | 0.80 | MAPT (0.41) | ADKPOLBALDH1A1KMT2AMAPT | |
| SCHEMBL29645888 | 0.80 | MAPT (0.55) | POLBKMT2AMAPTTP53LMNA | |
| SCHEMBL29645503 | 0.80 | ADORA3 (0.49) | POLBKMT2AHCRTR1MAPTTP53 | |
| SCHEMBL29645527 | 0.80 | MAPT (0.41) | ADKPOLBMAPTTP53LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114466850-A | [1,2,4] triazolo [1,5-C ] quinazolin-5-amines | 拜耳股份有限公司 | 2022-05-10 | — | — | CN | disclosed |