Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | RAD52 | P43351 | 1/20 | 0.38 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.38 |
| ▸ | CDC7 | O00311 | 1/20 | 0.37 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.37 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.37 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.37 |
| ▸ | PIM1 | P11309 | 1/20 | 0.37 |
| ▸ | GSK3A | P49840 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | NEK4 | P51957 | 1/20 | 0.37 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.37 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.37 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.37 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29645618 | 0.92 | ADORA3 (0.40) | LMNAGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL29645502 | 0.89 | RXFP1 (0.41) | LMNAGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL29645930 | 0.88 | POLB (0.38) | POLBRAD52SMARCA2KMT2AUHRF1 | |
| SCHEMBL29645864 | 0.88 | MAPT (0.40) | POLBRAD52SMARCA2KMT2AUHRF1 | |
| SCHEMBL29645839 | 0.88 | KDM4E (0.47) | POLBTP53MAPTKDM4EADORA3 | |
| SCHEMBL29646046 | 0.85 | ADORA1 (0.36) | PIM1ADORA3ADORA1 | |
| SCHEMBL31150076 | 0.84 | JAK2 (0.33) | MAPTADORA3ADORA1 | |
| SCHEMBL31149916 | 0.84 | ADORA3 (0.39) | CDC7MAP4K4PIM1GSK3AGSK3B | |
| SCHEMBL29645825 | 0.83 | TP53 (0.41) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL29645933 | 0.83 | TP53 (0.41) | KMT2ATP53MAPTADORA3ADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114466850-A | [1,2,4] triazolo [1,5-C ] quinazolin-5-amines | 拜耳股份有限公司 | 2022-05-10 | — | — | CN | claimed |