Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 7/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.40 |
| ▸ | TP53 | P04637 | 4/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.38 |
| ▸ | XDH | P47989 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GABRP | O00591 | 1/20 | 0.35 |
| ▸ | GABRD | O14764 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.35 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.35 |
| ▸ | GABRE | P78334 | 1/20 | 0.35 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29645443 | 0.92 | LMNA (0.40) | ADORA3ADORA1TP53MAPTLMNA | |
| SCHEMBL29645933 | 0.90 | TP53 (0.41) | ADORA3ADORA1TP53ADORA2AXDH | |
| SCHEMBL29645825 | 0.90 | TP53 (0.41) | ADORA3ADORA1TP53ADORA2AXDH | |
| SCHEMBL29645502 | 0.90 | RXFP1 (0.41) | TP53MAPTLMNAGABRPGABRD | |
| SCHEMBL29645839 | 0.90 | KDM4E (0.47) | ADORA3ADORA1TP53ADORA2AXDH | |
| SCHEMBL31149916 | 0.90 | ADORA3 (0.39) | ADORA3ADORA1TP53ADORA2AXDH | |
| SCHEMBL29645682 | 0.89 | ADORA3 (0.40) | ADORA3ADORA1TP53ADORA2AXDH | |
| SCHEMBL29645503 | 0.87 | ADORA3 (0.49) | ADORA3ADORA1TP53ADORA2AMAPT | |
| SCHEMBL29646046 | 0.85 | ADORA1 (0.36) | ADORA3ADORA1ADORA2A | |
| SCHEMBL31150076 | 0.84 | JAK2 (0.33) | ADORA3ADORA1ADORA2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114466850-A | [1,2,4] triazolo [1,5-C ] quinazolin-5-amines | 拜耳股份有限公司 | 2022-05-10 | — | — | CN | claimed |