Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | RAD52 | P43351 | 2/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 2/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.37 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.36 |
| ▸ | ADK | P55263 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29645906 | 0.86 | ADORA3 (0.36) | MAPTADORA3ADORA1ADORA2A | |
| SCHEMBL29645533 | 0.86 | MAPT (0.41) | MAPTPOLBRAD52RXFP1TP53 | |
| SCHEMBL29645665 | 0.85 | KDM4E (0.40) | MAPTPOLBRAD52RXFP1TP53 | |
| SCHEMBL29646149 | 0.84 | RXFP1 (0.38) | MAPTPOLBRAD52RXFP1TP53 | |
| SCHEMBL29646208 | 0.83 | MAPT (0.41) | MAPTPOLBRAD52RXFP1TP53 | |
| SCHEMBL29645980 | 0.83 | MAPT (0.41) | MAPTPOLBRAD52RXFP1TP53 | |
| SCHEMBL29645743 | 0.83 | GRM2 (0.39) | MAPTPOLBRAD52RXFP1TP53 | |
| SCHEMBL29645760 | 0.82 | MAPT (0.56) | MAPTPOLBRAD52RXFP1TP53 | |
| SCHEMBL29645527 | 0.82 | MAPT (0.41) | MAPTPOLBTP53ADK | |
| SCHEMBL29645636 | 0.82 | MAPT (0.47) | MAPTPOLBTHRBADORA3ADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114466850-A | [1,2,4] triazolo [1,5-C ] quinazolin-5-amines | 拜耳股份有限公司 | 2022-05-10 | — | — | CN | claimed |