Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 9/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 7/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 7/20 | 0.36 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 8/20 | 0.34 |
| ▸ | TNKS | O95271 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31149946 | 0.91 | ADORA3 (0.35) | ADORA3ADORA2AADORA1ADORA2BP2RX7 | |
| SCHEMBL29646105 | 0.89 | ADORA2A (0.38) | ADORA3ADORA2AADORA1ADORA2BP2RX7 | |
| SCHEMBL29645535 | 0.86 | MAPT (0.39) | ADORA3ADORA2AADORA1MAPT | |
| SCHEMBL29645864 | 0.82 | MAPT (0.40) | MAPT | |
| SCHEMBL31149981 | 0.80 | ADORA3 (0.33) | ADORA3ADORA2AADORA1ADORA2BP2RX7 | |
| SCHEMBL31150093 | 0.80 | ADORA2A (0.37) | ADORA3ADORA2AADORA1ADORA2BP2RX7 | |
| SCHEMBL29645933 | 0.80 | TP53 (0.41) | ADORA3ADORA2AADORA1MAPT | |
| SCHEMBL29645929 | 0.80 | KDM4E (0.47) | ADORA3ADORA2AADORA1MAPT | |
| SCHEMBL29645601 | 0.79 | MAPT (0.35) | ADORA3P2RX7MAPT | |
| SCHEMBL31150011 | 0.79 | CDK2 (0.36) | ADORA3ADORA2AADORA1ADORA2BP2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114466850-A | [1,2,4] triazolo [1,5-C ] quinazolin-5-amines | 拜耳股份有限公司 | 2022-05-10 | — | — | CN | claimed |