Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.41 |
| ▸ | TP53 | P04637 | 3/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | ADK | P55263 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29645674 | 0.92 | MAPT (0.41) | MAPTTP53RXFP1POLBADORA3 | |
| SCHEMBL29645868 | 0.91 | MAPT (0.37) | MAPTTP53RXFP1POLBADORA3 | |
| SCHEMBL29645527 | 0.90 | MAPT (0.41) | MAPTTP53POLBADK | |
| SCHEMBL29645913 | 0.89 | CCNC (0.39) | MAPT | |
| SCHEMBL29646169 | 0.88 | MAPT (0.37) | MAPTTP53RXFP1POLBADK | |
| SCHEMBL29645893 | 0.88 | MAPT (0.45) | MAPTTP53RXFP1POLBADORA3 | |
| SCHEMBL29646039 | 0.87 | C1R (0.40) | MAPTTP53RXFP1POLBADORA3 | |
| SCHEMBL29645638 | 0.86 | MAPT (0.40) | MAPTTP53RXFP1POLBADK | |
| SCHEMBL29645503 | 0.86 | ADORA3 (0.49) | MAPTTP53RXFP1POLBADORA3 | |
| SCHEMBL29645608 | 0.85 | MAPT (0.40) | MAPTTP53POLBADORA3ADK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114466850-A | [1,2,4] triazolo [1,5-C ] quinazolin-5-amines | 拜耳股份有限公司 | 2022-05-10 | — | — | CN | claimed |